ENSDARG00000053831


Danio rerio

Features
Gene ID: ENSDARG00000053831
  
Biological name :vtnb
  
Synonyms : vitronectin b / vtnb
  
Possible biological names infered from orthology : AC002094.3 / P04004 / P29788 / vitronectin / VTN
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 39067512
Gene end: 39081107
  
Corresponding Affymetrix probe sets: Dr.13466.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000070414
NCBI entrez gene - 403026     See in Manteia.
RefSeq - NM_001139461
RefSeq Peptide - NP_001132933
swissprot - F1Q5D8
ZFIN ID - ZDB-GENE-041116-1
Ensembl - ENSDARG00000053831
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VTNENSGALG00000003589Gallus gallus
 AC002094.3ENSG00000273171Homo sapiens
 VTNENSG00000109072Homo sapiens
 VtnENSMUSG00000017344Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vtna / vitronectin a / VTN* / P04004* / P29788* / AC002094.3* / vitronectin*ENSDARG0000005538853
prg4b / proteoglycan 4b / PRG4* / Q92954* / proteoglycan 4* / proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)*ENSDARG0000002816323
prg4a / proteoglycan 4a / PRG4* / Q92954* / proteoglycan 4* / proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)*ENSDARG0000001048222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001212  Somatomedin B domain
 IPR018487  Hemopexin-like repeats
 IPR020436  Somatomedin B, chordata


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006955 immune response IEA
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0030247 polysaccharide binding IEA


Pathways (from Reactome)
Pathway description
Molecules associated with elastic fibres
Integrin cell surface interactions
Syndecan interactions
ECM proteoglycans
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000032098 c8g / complement component 8, gamma polypeptide / Q8VCG4* / P07360* / complement C8 gamma chain* / Complement component C8 gamma chain *  / complex / reaction
 ENSDARG00000024537 emilin1a / elastin microfibril interfacer 1a / Q99K41* / Q9Y6C2* / EMILIN1* / elastin microfibril interfacer 1*  / complex / reaction
 ENSDARG00000071863 itgb1a / integrin, beta 1a / ITGB1* / P05556* / P09055* / Integrin beta-1 * / integrin subunit beta 1*  / complex / reaction
 ENSDARG00000012942 itgb5 / integrin, beta 5 / P18084* / integrin subunit beta 5*  / complex / reaction
 ENSDARG00000056795 serpine1 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 / P05121* / serpin family E member 1* / serine (or cysteine) peptidase inhibitor, cl...  / complex / reaction
 ENSDARG00000039517 c8b / complement component 8, beta polypeptide / P07358* / complement C8 beta chain*  / complex / reaction
 ENSDARG00000021004 c5 / complement component 5 / P01031* / complement C5*  / complex / reaction
 ENSDARG00000057121 c7b / complement component 7b / C7* / P10643* / complement C7* / complement component 7*  / complex / reaction
 ENSDARG00000039516 c8a / complement component 8, alpha polypeptide / P07357* / complement C8 alpha chain*  / complex / reaction
 ENSDARG00000090560 mfap5 / microfibril associated protein 5 / Q13361* / Q9QZJ6* / Microfibrillar-associated protein 5 *  / complex / reaction
 ENSDARG00000016319 c9 / complement component 9 / P02748* / complement C9*  / complex / reaction






 

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