ENSDARG00000059233


Danio rerio

Features
Gene ID: ENSDARG00000059233
  
Biological name :runx2b
  
Synonyms : runt-related transcription factor 2b / runx2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 43994848
Gene end: 44090660
  
Corresponding Affymetrix probe sets: DrAffx.2.6.S1_s_at (Zebrafish Array)   DrAffx.2.7.S1_at (Zebrafish Array)   NM_212862_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000076702
Ensembl peptide - ENSDARP00000076720
Ensembl peptide - ENSDARP00000112126
Ensembl peptide - ENSDARP00000048977
Ensembl peptide - ENSDARP00000076713
NCBI entrez gene - 405788     See in Manteia.
RefSeq - NM_212862
RefSeq Peptide - NP_998027
swissprot - F1QVK7
swissprot - F1QB94
swissprot - F1QVL8
swissprot - Q3L8U3
swissprot - Q4VW82
ZFIN ID - ZDB-GENE-040629-4
Ensembl - ENSDARG00000059233
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
runx2a / runt-related transcription factor 2a / RUNX2* / Q08775* / Q13950* / runt related transcription factor 2*ENSDARG0000004026178
runx3 / runt-related transcription factor 3 / Q13761* / Q64131*ENSDARG0000005282653
runx1 / runt-related transcription factor 1 / Q01196*ENSDARG0000008764652


Protein motifs (from Interpro)
Interpro ID Name
 IPR000040  Acute myeloid leukemia 1 protein (AML1)/Runt
 IPR008967  p53-like transcription factor, DNA-binding
 IPR012346  p53/RUNT-type transcription factor, DNA-binding domain superfamily
 IPR013524  Runt domain
 IPR013711  Runx, C-terminal domain
 IPR016554  Runt-related transcription factor RUNX
 IPR027384  Runx, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002062 chondrocyte differentiation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IGI
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0051216 cartilage development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042809 vitamin D receptor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite malformed , abnormal
Show

 ZFA:0000737 cranium cranium decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism ovate , abnormal
whole organism wholly dorsalized , abnormal
Show

 ZFA:0001115 trunk trunk decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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