ENSDARG00000052826
Danio rerio transcription runx3 runx cartilage factor regulation regulates domain p dna-binding differentiation dna-templated activity binding runt superfamily rna polymerase ii neuron dna signaling acute myeloid leukemia protein aml -like runt-type c-terminal runt-related
Features Gene ID: ENSDARG00000052826 Biological name :runx3 Synonyms : runt-related transcription factor 3 / Possible biological names infered from orthology : Q13761 / Species: Danio rerio Chr. number: 13 Strand: -1 Band: Gene start: 45092766 Gene end: 45225980 Corresponding Affymetrix probe sets: Dr.10668.1.S1_a_at (Zebrafish Array) Dr.10668.1.S2_at (Zebrafish Array) Cross references: Ensembl peptide - ENSDARP0000015593258127
See in Manteia .
F1QZI1 F6NM27 Q9DEA0 ZDB-GENE-000605-2 ENSDARG00000052826
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) runx2a / runt-related transcription factor 2a / RUNX2* / Q08775* / Q13950* / runt related transcription factor 2* ENSDARG00000040261 59 runx2b / runt-related transcription factor 2b ENSDARG00000059233 57 runx1 / runt-related transcription factor 1 / Q01196* ENSDARG00000087646 52
Protein motifs (from Interpro ) IPR000040 Acute myeloid leukemia 1 protein (AML1)/Runt IPR008967 p53-like transcription factor, DNA-binding IPR012346 p53/RUNT-type transcription factor, DNA-binding domain superfamily IPR013524 Runt domain IPR013711 Runx, C-terminal domain IPR016554 Runt-related transcription factor RUNX IPR027384 Runx, central domain superfamily
Gene Ontology (GO ) ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossification anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process ossificationossification anatomical structanatomical structure development cellular developmcellular developmental process nitrogen compoundnitrogen compound metabolic process biosynthetic procbiosynthetic process cellular metabolicellular metabolic process primary metabolicprimary metabolic process organic substanceorganic substance metabolic process DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcription factor activity organic cyclic compound binding heterocyclic compound binding ion binding carbohydrate derivative binding small molecule binding drug binding DNA-binding transcriDNA-binding transcription factor activity organic cyclic compoorganic cyclic compound binding heterocyclic compounheterocyclic compound binding ion bindingion binding carbohydrate derivatcarbohydrate derivative binding small molecule bindismall molecule binding drug bindingdrug binding cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cellcell organelleorganelle
Pathways (from Reactome )Phenotype (from MGI , Zfin or HPO ) ZFA:0000295 trigeminal ganglion trigeminal ganglion absent , abnormal
Show ZFA:0000737 cranium cranium decreased size , abnormal
Show ZFA:0001205 Meckel s cartilage Meckels cartilage aplastic , abnormal
Show ZFA:0001216 splanchnocranium splanchnocranium aplastic , abnormal
Show ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage aplastic , abnormal
Show ZFA:0001400 ceratohyal cartilage ceratohyal cartilage aplastic , abnormal
Show ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage aplastic , abnormal
Show ZFA:0001458 cranial cartilage cranial cartilage aplastic , abnormal
Show ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage aplastic , abnormal
Show ZFA:0001580 neurocranium neurocranium anterior region aplastic , abnormal
Show ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron absent , abnormal
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Interacting proteins (from Reactome ) ENSDARG00000014571 ctnnb1 / catenin (cadherin-associated protein), beta 1 / P35222* / catenin beta 1* / reaction / complex ENSDARG00000036096 smad3a / SMAD family member 3a / SMAD3* / Q8BUN5* / P84022* / SMAD family member 3* / Mothers against decapentaplegic homolog 3 * / complex / reaction ENSDARG00000022280 brd2a / bromodomain containing 2a / BRD2* / Q7JJ13* / P25440* / bromodomain containing 2* / Bromodomain-containing protein 2 * / complex / reaction ENSDARG00000033443 mdm2 / MDM2 oncogene, E3 ubiquitin protein ligase / P23804* / Q00987* / MDM2 proto-oncogene* / E3 ubiquitin-protein ligase Mdm2 * / complex / reaction ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53* / complex / reaction ENSDARG00000068401 yap1 / Q1L8J7 / Yes-associated protein 1 / P46937* / P46938* / complex / reaction ENSDARG00000101637 ccnd1 / Q90459 / cyclin D1 / P24385* / P25322* / G1/S-specific cyclin-D1 * / reaction / complex ENSDARG00000098349 hdac4 / histone deacetylase 4 / P56524* / Q6NZM9* / complex / reaction ENSDARG00000075226 smad4a / SMAD family member 4a / SMAD4* / Q13485* / SMAD family member 4* / complex / reaction ENSDARG00000008107 src / Q1JPZ3 / v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog / P12931* / P05480* / Neuronal proto-onco tyrosine-protein kinase Src * / SRC proto-oncogene, non-receptor tyr... / complex / reaction
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