ENSDARG00000060551


Danio rerio

Features
Gene ID: ENSDARG00000060551
  
Biological name :rps6ka5
  
Synonyms : ribosomal protein S6 kinase, polypeptide 5 / rps6ka5
  
Possible biological names infered from orthology : O75582 / Q8C050 / ribosomal protein S6 kinase A5
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 38393189
Gene end: 38442362
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000079873
NCBI entrez gene - 565173     See in Manteia.
swissprot - E7FE05
ZFIN ID - ZDB-GENE-130530-693
Ensembl - ENSDARG00000060551
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5F3L1ENSGALG00000030580Gallus gallus
 O75582ENSG00000100784Homo sapiens
 Q8C050ENSMUSG00000021180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rps6ka4 / ribosomal protein S6 kinase, polypeptide 4 / O75676* / Q9Z2B9* / ribosomal protein S6 kinase A4*ENSDARG0000004443661
rps6ka2 / ribosomal protein S6 kinase, polypeptide 2 / Q15349* / ribosomal protein S6 kinase A2*ENSDARG0000002846938
rps6ka3a / ribosomal protein S6 kinase a, polypeptide 3aENSDARG0000003555638
rps6kal / ribosomal protein S6 kinase a, like / Q9UK32* / RPS6KA6* / ribosomal protein S6 kinase A6* / ribosomal protein S6 kinase polypeptide 6*ENSDARG0000003757438
rps6ka1 / ribosomal protein S6 kinase a, polypeptide 1 / P18653* / Q15418* / ribosomal protein S6 kinase A1* / ribosomal protein S6 kinase polypeptide 1*ENSDARG0000003343737
rps6ka3b / ribosomal protein S6 kinase, polypeptide 3bENSDARG0000005792737
rps6kb1b / ribosomal protein S6 kinase b, polypeptide 1b / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000005823024
rps6kb1a / ribosomal protein S6 kinase b, polypeptide 1a / Q8BSK8* / P23443* / RPS6KB1* / ribosomal protein S6 kinase B1* / ribosomal protein S6 kinase, polypeptide 1*ENSDARG0000001839923
stk32a / serine/threonine kinase 32A / Q8BGW6* / Q8WU08* / Serine/threonine-protein kinase 32A *ENSDARG000000794999


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016239  Ribosomal protein S6 kinase II
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
ERK/MAPK targets
CREB phosphorylation
NCAM signaling for neurite out-growth
CD209 (DC-SIGN) signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000045836 mapk11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*  / reaction
 ENSDARG00000028721 mapk14b / mitogen-activated protein kinase 14b / Q16539* / MAPK14* / P47811* / mitogen-activated protein kinase 14*  / reaction
 ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction
 ENSDARG00000000857 Q9DGE2 / mapk14a / mitogen-activated protein kinase 14a / P47811* / Q16539* / MAPK14* / mitogen-activated protein kinase 14*  / reaction
 ENSDARG00000044301 atf1 / activating transcription factor 1 / P18846* / P81269* / Cyclic AMP-dependent transcription factor ATF-1 *  / reaction
 ENSDARG00000098696 rela / v-rel avian reticuloendotheliosis viral oncogene homolog A / Q04206* / RELA proto-oncogene, NF-kB subunit*  / reaction
 ENSDARG00000105261 nfkb1 / nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 / P25799* / P19838* / nuclear factor kappa B subunit 1* / Nuclear factor NF-kappa-B p105 subunit Nuclear factor ...  / reaction
 ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr