ENSDARG00000063663


Danio rerio

Features
Gene ID: ENSDARG00000063663
  
Biological name :clp1
  
Synonyms : cleavage and polyadenylation factor I subunit 1 / clp1 / E7F3I6
  
Possible biological names infered from orthology : Polyribonucleotide 5-hydroxyl-kinase Clp1 / Q92989 / Q99LI9
  
Species: Danio rerio
  
Chr. number: 14
Strand: 1
Band:
Gene start: 48982236
Gene end: 48998631
  
Corresponding Affymetrix probe sets: Dr.15982.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000087664
NCBI entrez gene - 565621     See in Manteia.
swissprot - E7F3I6
ZFIN ID - ZDB-GENE-030131-5306
Ensembl - ENSDARG00000063663
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CLP1ENSGALG00000007370Gallus gallus
 CLP1ENSG00000172409Homo sapiens
 Clp1ENSMUSG00000027079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010655  Pre-mRNA cleavage complex subunit Clp1, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028606  Polyribonucleotide 5-hydroxyl-kinase Clp1
 IPR032319  Polyribonucleotide 5"-hydroxyl-kinase Clp1, P-loop domain
 IPR032324  Clp1, N-terminal beta-sandwich domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation IBA
 biological_processGO:0006379 mRNA cleavage IBA
 biological_processGO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0008033 tRNA processing IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation IMP
 biological_processGO:0021695 cerebellar cortex development ISS
 biological_processGO:0031124 mRNA 3"-end processing IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005849 mRNA cleavage factor complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046404 ATP-dependent polydeoxyribonucleotide 5"-hydroxyl-kinase activity IEA
 molecular_functionGO:0051731 polynucleotide 5"-hydroxyl-kinase activity IBA
 molecular_functionGO:0051736 ATP-dependent polyribonucleotide 5"-hydroxyl-kinase activity IMP


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain degenerate , abnormal
Show

 ZFA:0000029 hindbrain hindbrain apoptotic , abnormal
Show

 ZFA:0000101 diencephalon diencephalon apoptotic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000128 midbrain midbrain apoptotic , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001114 head head deformed , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
Show

 ZFA:0009052 motor neuron motor neuron morphology , abnormal
motor neuron broken , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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