ENSDARG00000063706


Danio rerio

Features
Gene ID: ENSDARG00000063706
  
Biological name :pde8b
  
Synonyms : pde8b / phosphodiesterase 8B
  
Possible biological names infered from orthology : AC022414.1 / E9Q4S1 / High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B / high affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B isoform 11 / O95263
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 7642403
Gene end: 7691293
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000087771
Ensembl peptide - ENSDARP00000117836
swissprot - E7F286
swissprot - F1QXX7
ZFIN ID - ZDB-GENE-091117-3
Ensembl - ENSDARG00000063706
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000004339Gallus gallus
 AC022414.1ENSG00000284762Homo sapiens
 PDE8BENSG00000113231Homo sapiens
 Pde8bENSMUSG00000021684Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pde8a / phosphodiesterase 8A / O60658*ENSDARG0000008794148
pde4cb / phosphodiesterase 4C, cAMP-specific b / PDE4C* / Q3UEI1* / Q08493* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSDARG0000000241118
pde4ca / phosphodiesterase 4C, cAMP-specific a / PDE4C* / Q3UEI1* / Q08493* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSDARG0000001322118
pde4a / phosphodiesterase 4A, cAMP-specific / O89084* / P27815* / phosphodiesterase 4A*ENSDARG0000003234418
pde4ba / phosphodiesterase 4B, cAMP-specific a / PDE4B* / Q07343* / phosphodiesterase 4B* / phosphodiesterase 4B, cAMP specific*ENSDARG0000003286818
pde4bb / phosphodiesterase 4B, cAMP-specific b / PDE4B* / Q07343* / phosphodiesterase 4B* / phosphodiesterase 4B, cAMP specific*ENSDARG0000007423318
pde4d / phosphodiesterase 4D, cAMP-specific / Q01063* / Q08499* / phosphodiesterase 4D* / cAMP-specific 3,5-cyclic phosphodiesterase 4D *ENSDARG0000003276117
pde1a / phosphodiesterase 1A, calmodulin-dependent / P54750* / phosphodiesterase 1A*ENSDARG0000006087515
CABZ01067973.1 / PDE1C* / Q14123* / phosphodiesterase 1C*ENSDARG0000009039815
pde7a / phosphodiesterase 7A / P70453* / Q13946* / High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A *ENSDARG0000004530513


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR013767  PAS fold
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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