ENSDARG00000087941


Danio rerio

Features
Gene ID: ENSDARG00000087941
  
Biological name :pde8a
  
Synonyms : pde8a / phosphodiesterase 8A
  
Possible biological names infered from orthology : High affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8A / O60658 / O88502
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 14710
Gene end: 33344
  
Corresponding Affymetrix probe sets: Dr.11295.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000107237
swissprot - E7F5I1
ZFIN ID - ZDB-GENE-070112-622
Ensembl - ENSDARG00000087941
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PDE8AENSGALG00000005992Gallus gallus
 PDE8AENSG00000073417Homo sapiens
 Pde8aENSMUSG00000025584Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pde8b / phosphodiesterase 8B / O95263* / AC022414.1* / high affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B isoform 11 *ENSDARG0000006370660
pde4cb / phosphodiesterase 4C, cAMP-specific b / PDE4C* / Q3UEI1* / Q08493* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSDARG0000000241117
pde4ca / phosphodiesterase 4C, cAMP-specific a / PDE4C* / Q3UEI1* / Q08493* / AC008397.2* / phosphodiesterase 4C* / cAMP-specific 3,5-cyclic phosphodiesterase 4C *ENSDARG0000001322117
pde4a / phosphodiesterase 4A, cAMP-specific / O89084* / P27815* / phosphodiesterase 4A*ENSDARG0000003234417
pde4ba / phosphodiesterase 4B, cAMP-specific a / PDE4B* / Q07343* / phosphodiesterase 4B* / phosphodiesterase 4B, cAMP specific*ENSDARG0000003286817
pde4bb / phosphodiesterase 4B, cAMP-specific b / PDE4B* / Q07343* / phosphodiesterase 4B* / phosphodiesterase 4B, cAMP specific*ENSDARG0000007423317
pde4d / phosphodiesterase 4D, cAMP-specific / Q01063* / Q08499* / phosphodiesterase 4D* / cAMP-specific 3,5-cyclic phosphodiesterase 4D *ENSDARG0000003276116
pde1a / phosphodiesterase 1A, calmodulin-dependent / P54750* / phosphodiesterase 1A*ENSDARG0000006087514
CABZ01067973.1 / PDE1C* / Q14123* / phosphodiesterase 1C*ENSDARG0000009039814
pde7a / phosphodiesterase 7A / P70453* / Q13946* / High affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A *ENSDARG0000004530513


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR011006  CheY-like superfamily
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000160 phosphorelay signal transduction system IEA
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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