ENSDARG00000068460


Danio rerio

Features
Gene ID: ENSDARG00000068460
  
Biological name :otog
  
Synonyms : otog / otogelin
  
Possible biological names infered from orthology : Q6ZRI0
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 39463050
Gene end: 39537292
  
Corresponding Affymetrix probe sets: Dr.7234.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000142662
Ensembl peptide - ENSDARP00000142739
swissprot - A0A1D5NS53
swissprot - A0A1D5NSC6
ZFIN ID - ZDB-GENE-120228-1
Ensembl - ENSDARG00000068460
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OTOGENSGALG00000006208Gallus gallus
 OTOGENSG00000188162Homo sapiens
 OtogENSMUSG00000009487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
otogl / otogelin-like / F7A4A7* / Q3ZCN5* / Otogelin-like protein *ENSDARG0000008875035
muc5.1 / mucin 5.1, oligomeric mucus/gel-forming / MUC5B* / MUC5AC* / P98088* / Q9HC84* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSDARG0000007033122
muc5.2 / mucin 5.2 / MUC5B* / MUC5AC* / P98088* / Q9HC84* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSDARG0000005855621
muc5.3 / mucin 5.3 / MUC5B* / MUC5AC* / P98088* / Q9HC84* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSDARG0000009947021
vwf / von Willebrand factor / P04275*ENSDARG0000007723119
scospondin / subcommissural organ spondin / SSPO* / Q8CG65* / SCO-spondin*ENSDARG0000006785916
zanl / zonadhesin, like / ZAN* / zonadhesin* / zonadhesin (gene/pseudogene)*ENSDARG0000005678113
si:ch211-39f2.3ENSDARG0000009753913
CABZ01080550.1ENSDARG0000010062113
si:dkey-65b12.6 / FCGBP* / 9530053A07Rik* / RIKEN cDNA 9530053A07 gene* / Fc fragment of IgG binding protein*ENSDARG0000007683012
tecta / tectorin alpha / O08523* / O75443*ENSDARG0000005955811
si:dkey-239b22.1ENSDARG0000003158810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001007  VWFC domain
 IPR001846  von Willebrand factor, type D domain
 IPR002919  Trypsin Inhibitor-like, cysteine rich domain
 IPR006207  Cystine knot, C-terminal
 IPR007934  Alpha-L-arabinofuranosidase B, arabinose-binding domain
 IPR014853  Uncharacterised domain, cysteine-rich
 IPR029034  Cystine-knot cytokine
 IPR030105  Otogelin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008344 adult locomotory behavior IEA
 biological_processGO:0032475 otolith formation IMP
 biological_processGO:0035889 otolith tethering IGI
 biological_processGO:0046373 L-arabinose metabolic process IEA
 biological_processGO:0048840 otolith development IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0046556 alpha-L-arabinofuranosidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000051 otic vesicle otic vesicle has fewer parts of type otolith , abnormal
otic vesicle otolith tethering delayed , abnormal
otic vesicle otolith formation delayed , abnormal
otic vesicle otolith tethering arrested , abnormal
Show

 ZFA:0000217 inner ear inner ear has fewer parts of type otolith , abnormal
inner ear quality , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000530 lapillus lapillus absent , abnormal
Show

 ZFA:0000700 utricle utricle lacks all parts of type lapillus , abnormal
utricle otolith formation arrested , abnormal
utricle has fewer parts of type lapillus , abnormal
utricle otolith formation delayed , abnormal
Show

 ZFA:0001094 whole organism whole organism balance , abnormal
whole organism circling , abnormal
Show

 ZFA:0001617 otolith otolith quality , abnormal
otolith increased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr