ENSDARG00000068478


Danio rerio

Features
Gene ID: ENSDARG00000068478
  
Biological name :gpx4a
  
Synonyms : glutathione peroxidase 4a / gpx4a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 17589608
Gene end: 17611742
  
Corresponding Affymetrix probe sets: Dr.4983.1.S1_at (Zebrafish Array)   NM_001007282_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000120856
Ensembl peptide - ENSDARP00000089830
Ensembl peptide - ENSDARP00000142217
Ensembl peptide - ENSDARP00000152224
NCBI entrez gene - 352928     See in Manteia.
RefSeq - NM_001007282
RefSeq Peptide - NP_001007283
swissprot - F6NPA3
swissprot - A0A140LG39
swissprot - F6NSX3
swissprot - Q6DHK6
ZFIN ID - ZDB-GENE-030410-2
Ensembl - ENSDARG00000068478
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpx4b / glutathione peroxidase 4b / GPX4* / P36969* / glutathione peroxidase 4*ENSDARG0000007683671
gpx8 / glutathione peroxidase 8 (putative) / Q8TED1*ENSDARG0000001330233
gpx3 / glutathione peroxidase 3 / GPX6* / GPX5* / P46412* / Q91WR8* / P59796* / O75715* / P21765* / P22352* / glutathione peroxidase 6* / glutathione peroxidase 5* / Epididymal secretory gl...ENSDARG0000004334233
gpx1a / glutathione peroxidase 1a / GPX2* / P18283* / glutathione peroxidase 2*ENSDARG0000001814631
gpx7 / glutathione peroxidase 7 / Q96SL4*ENSDARG0000009151131
gpx1b / glutathione peroxidase 1b / GPX2* / P18283* / glutathione peroxidase 2*ENSDARG0000000620725
si:ch73-111m19.2ENSDARG0000000307722


Protein motifs (from Interpro)
Interpro ID Name
 IPR000889  Glutathione peroxidase
 IPR012336  Thioredoxin-like fold
 IPR029759  Glutathione peroxidase active site
 IPR029760  Glutathione peroxidase conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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