ENSDARG00000018146


Danio rerio

Features
Gene ID: ENSDARG00000018146
  
Biological name :gpx1a
  
Synonyms : glutathione peroxidase 1a / gpx1a
  
Possible biological names infered from orthology : glutathione peroxidase 2 / GPX2 / P18283
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 36048579
Gene end: 36156971
  
Corresponding Affymetrix probe sets: Dr.7977.1.S1_at (Zebrafish Array)   NM_001007281_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000020656
Ensembl peptide - ENSDARP00000112679
NCBI entrez gene - 352926     See in Manteia.
RefSeq - NM_001007281
RefSeq Peptide - NP_001007282
swissprot - F6NYT7
swissprot - B0V1T0
ZFIN ID - ZDB-GENE-030410-1
Ensembl - ENSDARG00000018146
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GPX2ENSGALG00000042031Gallus gallus
 GPX2ENSG00000176153Homo sapiens
 Gpx2ENSMUSG00000042808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gpx1b / glutathione peroxidase 1b / GPX2* / P18283* / glutathione peroxidase 2*ENSDARG0000000620759
gpx3 / glutathione peroxidase 3 / GPX6* / GPX5* / P46412* / Q91WR8* / P59796* / O75715* / P21765* / P22352* / glutathione peroxidase 6* / glutathione peroxidase 5* / Epididymal secretory gl...ENSDARG0000004334242
si:ch73-111m19.2ENSDARG0000000307736
gpx4b / glutathione peroxidase 4b / GPX4* / P36969* / glutathione peroxidase 4*ENSDARG0000007683631
gpx4a / glutathione peroxidase 4aENSDARG0000006847830
gpx7 / glutathione peroxidase 7 / Q96SL4*ENSDARG0000009151125
gpx8 / glutathione peroxidase 8 (putative) / Q8TED1*ENSDARG0000001330224


Protein motifs (from Interpro)
Interpro ID Name
 IPR000889  Glutathione peroxidase
 IPR012336  Thioredoxin-like fold
 IPR029759  Glutathione peroxidase active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 molecular_functionGO:0004601 peroxidase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of 12-eicosatetraenoic acid derivatives
Detoxification of Reactive Oxygen Species
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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