ENSDARG00000069463


Danio rerio

Features
Gene ID: ENSDARG00000069463
  
Biological name :alox12
  
Synonyms : alox12 / arachidonate 12-lipoxygenase
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 26029672
Gene end: 26047946
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091900
NCBI entrez gene - 322732     See in Manteia.
RefSeq - NM_199618
RefSeq Peptide - NP_955912
swissprot - Q7T2A9
ZFIN ID - ZDB-GENE-030131-1452
Ensembl - ENSDARG00000069463
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
alox5a / arachidonate 5-lipoxygenase a / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000005727344
alox5b.3 / arachidonate 5-lipoxygenase b, tandem duplicate 3 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000006996643
alox5b.2 / arachidonate 5-lipoxygenase b, tandem duplicate 2 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000004308941
alox5b.1 / arachidonate 5-lipoxygenase b, tandem duplicate 1 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000004308539
si:dkey-17e16.9 / ALOX12* / P18054* / P39654* / P39655* / P55249* / ALOX15* / P16050* / Alox12e* / arachidonate 12-lipoxygenase* / arachidonate 15-lipoxygenase* / arachidonate lipoxygenase,...ENSDARG0000007378139
zgc:152891 / Alox8* / ALOXE3* / O15296* / O35936* / O70582* / O75342* / Q9BYJ1* / Q9WV07* / ALOX12B* / ALOX15B* / arachidonate lipoxygenase 3* / Arachidonate 8S-lipoxygenase * / arachidonat...ENSDARG0000001678936


Protein motifs (from Interpro)
Interpro ID Name
 IPR000907  Lipoxygenase
 IPR001024  PLAT/LH2 domain
 IPR001885  Lipoxygenase, mammalian
 IPR013819  Lipoxygenase, C-terminal
 IPR020834  Lipoxygenase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0004052 arachidonate 12-lipoxygenase activity IMP
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show

 ZFA:0000035 lens lens composition , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0000101 diencephalon diencephalon decreased size , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye decreased diameter , abnormal
Show

 ZFA:0000128 midbrain midbrain decreased size , abnormal
Show

 ZFA:0000155 somite somite unstructured , abnormal
Show

 ZFA:0001114 head head hypoplastic , abnormal
Show

 ZFA:0001117 post-vent region post-vent region bent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr