ENSDARG00000073781


Danio rerio

Features
Gene ID: ENSDARG00000073781
  
Biological name :si:dkey-17e16.9
  
Synonyms : si:dkey-17e16.9
  
Possible biological names infered from orthology : ALOX12 / Alox12e / ALOX15 / arachidonate 12-lipoxygenase / arachidonate 12-lipoxygenase, 12S type / arachidonate 15-lipoxygenase / arachidonate lipoxygenase, epidermal / P16050 / P18054 / P39654 / P39655 / P55249
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 25544882
Gene end: 25555355
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000113298
swissprot - E9QGC1
ZFIN ID - ZDB-GENE-091118-123
Ensembl - ENSDARG00000073781
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALOX12ENSG00000108839Homo sapiens
 ALOX15ENSG00000161905Homo sapiens
 Alox12ENSMUSG00000000320Mus musculus
 Alox15ENSMUSG00000018924Mus musculus
 P55249ENSMUSG00000018907Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
alox12 / arachidonate 12-lipoxygenaseENSDARG0000006946339
zgc:152891 / Alox8* / ALOXE3* / O15296* / O35936* / O70582* / O75342* / Q9BYJ1* / Q9WV07* / ALOX12B* / ALOX15B* / arachidonate lipoxygenase 3* / Arachidonate 8S-lipoxygenase * / arachidonat...ENSDARG0000001678938
alox5b.2 / arachidonate 5-lipoxygenase b, tandem duplicate 2 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000004308937
alox5a / arachidonate 5-lipoxygenase a / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000005727337
alox5b.3 / arachidonate 5-lipoxygenase b, tandem duplicate 3 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000006996636
alox5b.1 / arachidonate 5-lipoxygenase b, tandem duplicate 1 / ALOX5* / P09917* / P48999* / arachidonate 5-lipoxygenase*ENSDARG0000004308534


Protein motifs (from Interpro)
Interpro ID Name
 IPR000907  Lipoxygenase
 IPR001024  PLAT/LH2 domain
 IPR001885  Lipoxygenase, mammalian
 IPR013819  Lipoxygenase, C-terminal
 IPR020834  Lipoxygenase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Leukotrienes (LT) and Eoxins (EX)
Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
Synthesis of Lipoxins (LX)
Synthesis of 12-eicosatetraenoic acid derivatives
Synthesis of 15-eicosatetraenoic acid derivatives
Biosynthesis of DHA-derived SPMs
Biosynthesis of protectins
Biosynthesis of E-series 18(S)-resolvins
Biosynthesis of E-series 18(R)-resolvins
Biosynthesis of DPAn-6 SPMs
Biosynthesis of DPAn-3-derived protectins and resolvins
Biosynthesis of DPAn-3-derived maresins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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