ENSDARG00000069706


Danio rerio

Features
Gene ID: ENSDARG00000069706
  
Biological name :prmt6
  
Synonyms : prmt6 / protein arginine methyltransferase 6
  
Possible biological names infered from orthology : protein arginine N-methyltransferase 6 / Q6NZB1 / Q96LA8
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 29352039
Gene end: 29353521
  
Corresponding Affymetrix probe sets: Dr.13593.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000106043
NCBI entrez gene - 448867     See in Manteia.
RefSeq - NM_001163988
RefSeq Peptide - NP_001157460
swissprot - F1QC81
ZFIN ID - ZDB-GENE-040914-7
Ensembl - ENSDARG00000069706
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRMT6ENSG00000198890Homo sapiens
 Prmt6ENSMUSG00000049300Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prmt1 / protein arginine methyltransferase 1 / Q99873* / Q9JIF0* / protein arginine N-methyltransferase 1*ENSDARG0000001024639
PRMT8 / protein arginine methyltransferase 8 / Q9NR22*ENSDARG0000004063337
Q5RGQ2 / prmt8b / protein arginine methyltransferase 8b / PRMT8* / Q6PAK3* / Q9NR22* / protein arginine methyltransferase 8* / protein arginine N-methyltransferase 8*ENSDARG0000004576036
prmt2 / protein arginine methyltransferase 2 / P55345* / protein arginine N-methyltransferase 2*ENSDARG0000006321236
prmt3 / protein arginine methyltransferase 3 / O60678* / Q922H1* / protein arginine N-methyltransferase 3*ENSDARG0000001979135
carm1 / Q6DC04 / coactivator-associated arginine methyltransferase 1 / Q9WVG6* / Q86X55* / Histone-arginine methyltransferase CARM1 *ENSDARG0000001869830
carm1l / coactivator-associated arginine methyltransferase 1, likeENSDARG0000009153129


Protein motifs (from Interpro)
Interpro ID Name
 IPR025799  Protein arginine N-methyltransferase
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006479 protein methylation IEA
 biological_processGO:0032259 methylation IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
RMTs methylate histone arginines
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure amount , ameliorated
anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000059812 sin3ab / SIN3 transcription regulator family member Ab / SIN3A* / Q96ST3* / Q60520* / SIN3 transcription regulator family member A* / Mus musculus transcriptional regulator, SIN3A (yeast) (...  / complex / reaction
 ENSDARG00000079716 sin3aa / SIN3 transcription regulator family member Aa / SIN3A* / Q96ST3* / Q60520* / SIN3 transcription regulator family member A* / Mus musculus transcriptional regulator, SIN3A (yeast) (...  / complex / reaction
 ENSDARG00000015427 hdac1 / histone deacetylase 1 / O09106* / Q13547* / Gm10093*  / complex / reaction
 ENSDARG00000068436 Q6PI20 / h3f3b.1 / H3 histone, family 3B.1 / H3F3B* / H3F3C* / P84243* / Q6NXT2* / H3 histone family member 3C* / H3 histone family member 3B*  / complex
 ENSDARG00000105345 zgc:173552  / complex
 ENSDARG00000105359 Q4QRF4 / FP325123.1 / Histone H3.2   / complex
 ENSDARG00000087646 runx1 / runt-related transcription factor 1 / Q01196*  / complex / reaction






 

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