ENSDARG00000070107


Danio rerio

Features
Gene ID: ENSDARG00000070107
  
Biological name :six7
  
Synonyms : six7 / SIX homeobox 7
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 7401692
Gene end: 7420301
  
Corresponding Affymetrix probe sets: Dr.12825.1.A1_at (Zebrafish Array)   Dr.617.1.S1_at (Zebrafish Array)   NM_131354_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000093395
NCBI entrez gene - 30625     See in Manteia.
RefSeq - NM_131354
RefSeq Peptide - NP_571429
swissprot - O93282
ZFIN ID - ZDB-GENE-990825-28
Ensembl - ENSDARG00000070107
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
six3a / SIX homeobox 3a / SIX3* / Q62233* / O95343* / SIX homeobox 3* / Homeobox protein SIX3 *ENSDARG0000005800868
six6b / SIX homeobox 6b / SIX6* / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSDARG0000003131667
six6a / SIX homeobox 6a / SIX6* / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSDARG0000002518766
six3b / SIX homeobox 3b / SIX3* / Q62233* / O95343* / SIX homeobox 3* / Homeobox protein SIX3 *ENSDARG0000005487965
six2a / SIX homeobox 2a / SIX2* / Q9NPC8* / Q62232* / SIX homeobox 2* / Homeobox protein SIX2 *ENSDARG0000005800452
six2b / SIX homeobox 2b / SIX2* / Q9NPC8* / Q62232* / SIX homeobox 2* / Homeobox protein SIX2 *ENSDARG0000005487851
six1b / Q6NZ04 / SIX homeobox 1b / SIX1* / Q62231* / Q15475* / SIX homeobox 1* / Homeobox protein SIX1 *ENSDARG0000002647350
six1a / Q6DHF9 / SIX homeobox 1a / SIX1* / Q62231* / Q15475* / SIX homeobox 1* / Homeobox protein SIX1 *ENSDARG0000003930450
six4a / SIX homeobox 4a / SIX4* / Q9UIU6* / Q61321* / SIX homeobox 4* / Homeobox protein SIX4 *ENSDARG0000000469545
six9 / SIX homeobox 9ENSDARG0000006840745
six4b / SIX homeobox 4b / SIX4* / Q9UIU6* / Q61321* / SIX homeobox 4* / Homeobox protein SIX4 *ENSDARG0000003198343
six5 / SIX homeobox 5 / P70178* / Q8N196* / Homeobox protein SIX5 *ENSDARG0000006840641


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR031701  Homeobox protein SIX1, N-terminal SD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IGI
 biological_processGO:0046549 retinal cone cell development IMP
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer apoptotic process increased occurrence , abnormal
Show

 ZFA:0000107 eye eye aplastic , abnormal
eye decreased size , abnormal
Show

 ZFA:0000119 retinal inner nuclear layer retinal inner nuclear layer apoptotic process increased occurrence , abnormal
Show

 ZFA:0000137 optic stalk optic stalk decreased size , abnormal
Show

 ZFA:0000213 habenula habenula asymmetrical , abnormal
Show

 ZFA:0001360 parapineal organ parapineal organ right side of epiphysis , abnormal
parapineal organ mislocalised anteriorly , abnormal
Show

 ZFA:0001464 retinal outer nuclear layer retinal outer nuclear layer retinal rod cell increased amount , abnormal
retinal outer nuclear layer cell proliferation temporally extended , abnormal
retinal outer nuclear layer apoptotic process increased occurrence , abnormal
Show

 ZFA:0009222 blue sensitive photoreceptor cell blue sensitive photoreceptor cell decreased amount , abnormal
Show

 ZFA:0009223 green sensitive photoreceptor cell green sensitive photoreceptor cell decreased amount , abnormal
Show

 ZFA:0009275 retinal rod cell retinal rod cell increased amount , abnormal
retinal rod cell cell proliferation increased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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