ENSDARG00000058004


Danio rerio

Features
Gene ID: ENSDARG00000058004
  
Biological name :six2a
  
Synonyms : six2a / SIX homeobox 2a
  
Possible biological names infered from orthology : Homeobox protein SIX2 / Q62232 / Q9NPC8 / SIX2 / SIX homeobox 2
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 10232695
Gene end: 10235565
  
Corresponding Affymetrix probe sets: Dr.8955.1.S1_at (Zebrafish Array)   NM_131783_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000075251
NCBI entrez gene - 83415     See in Manteia.
RefSeq - NM_131783
RefSeq Peptide - NP_571858
swissprot - Q98TH1
ZFIN ID - ZDB-GENE-010412-1
Ensembl - ENSDARG00000058004
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SIX2ENSGALG00000023303Gallus gallus
 SIX2ENSG00000170577Homo sapiens
 Six2ENSMUSG00000024134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
six2b / SIX homeobox 2b / SIX2* / Q9NPC8* / Q62232* / SIX homeobox 2* / Homeobox protein SIX2 *ENSDARG0000005487883
six1b / Q6NZ04 / SIX homeobox 1b / SIX1* / Q62231* / Q15475* / SIX homeobox 1* / Homeobox protein SIX1 *ENSDARG0000002647375
six1a / Q6DHF9 / SIX homeobox 1a / SIX1* / Q62231* / Q15475* / SIX homeobox 1* / Homeobox protein SIX1 *ENSDARG0000003930472
six4a / SIX homeobox 4a / SIX4* / Q9UIU6* / Q61321* / SIX homeobox 4* / Homeobox protein SIX4 *ENSDARG0000000469550
six9 / SIX homeobox 9ENSDARG0000006840750
six6a / SIX homeobox 6a / SIX6* / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSDARG0000002518749
six6b / SIX homeobox 6b / SIX6* / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSDARG0000003131649
six4b / SIX homeobox 4b / SIX4* / Q9UIU6* / Q61321* / SIX homeobox 4* / Homeobox protein SIX4 *ENSDARG0000003198348
six3a / SIX homeobox 3a / SIX3* / Q62233* / O95343* / SIX homeobox 3* / Homeobox protein SIX3 *ENSDARG0000005800848
six3b / SIX homeobox 3b / SIX3* / Q62233* / O95343* / SIX homeobox 3* / Homeobox protein SIX3 *ENSDARG0000005487946
six7 / SIX homeobox 7ENSDARG0000007010746
six5 / SIX homeobox 5 / P70178* / Q8N196* / Homeobox protein SIX5 *ENSDARG0000006840645


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR031701  Homeobox protein SIX1, N-terminal SD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0048793 pronephros development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm increased width , abnormal
Show

 ZFA:0000135 notochord notochord aplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
whole organism spindle-shaped , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head aplastic , abnormal
Show

 ZFA:0001557 pronephric glomerulus pronephric glomerulus morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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