ENSGALG00000023303


Gallus gallus

Features
Gene ID: ENSGALG00000023303
  
Biological name :SIX2
  
Synonyms : homeobox protein SIX2 / SIX2
  
Possible biological names infered from orthology : Q62232 / Q9NPC8 / SIX homeobox 2
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 25957358
Gene end: 25960417
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000043451
NCBI entrez gene - 724086     See in Manteia.
RefSeq - NM_001044695
RefSeq Peptide - NP_001038160
swissprot - R4GMI5
Ensembl - ENSGALG00000023303
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 six2aENSDARG00000058004Danio rerio
 six2bENSDARG00000054878Danio rerio
 SIX2ENSG00000170577Homo sapiens
 Six2ENSMUSG00000024134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIX1 / SIX homeobox 1 / Q15475* / Q62231* / Homeobox protein SIX1 *ENSGALG0000002940177
SIX3 / SIX homeobox 3 / O95343* / Q62233* / Homeobox protein SIX3 *ENSGALG0000003225950
SIX4 / SIX homeobox 4 / Q61321* / Q9UIU6* / Homeobox protein SIX4 *ENSGALG0000001738948
SIX6 / O93307 / Homeobox protein SIX6 / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSGALG0000002035948


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR031701  Homeobox protein SIX1, N-terminal SD domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0002062 chondrocyte differentiation IEA
 biological_processGO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0007501 mesodermal cell fate specification IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009948 anterior/posterior axis specification IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030278 regulation of ossification IEA
 biological_processGO:0032330 regulation of chondrocyte differentiation IEA
 biological_processGO:0042474 middle ear morphogenesis IEA
 biological_processGO:0045596 negative regulation of cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048557 embryonic digestive tract morphogenesis IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IEA
 biological_processGO:0072006 nephron development IEA
 biological_processGO:0072028 nephron morphogenesis IEA
 biological_processGO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis IEA
 biological_processGO:0072137 condensed mesenchymal cell proliferation IEA
 biological_processGO:0072161 mesenchymal cell differentiation involved in kidney development IEA
 biological_processGO:0090189 regulation of branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0097168 mesenchymal stem cell proliferation IEA
 biological_processGO:1902732 positive regulation of chondrocyte proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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