ENSGALG00000032259


Gallus gallus

Features
Gene ID: ENSGALG00000032259
  
Biological name :SIX3
  
Synonyms : SIX3 / SIX homeobox 3
  
Possible biological names infered from orthology : Homeobox protein SIX3 / O95343 / Q62233
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 25897937
Gene end: 25901177
  
Corresponding Affymetrix probe sets: Gga.291.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058342
RefSeq - XM_015283827
swissprot - A0A1D5PZD1
Ensembl - ENSGALG00000032259
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 six3aENSDARG00000058008Danio rerio
 six3bENSDARG00000054879Danio rerio
 SIX3ENSG00000138083Homo sapiens
 Six3ENSMUSG00000038805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SIX6 / O93307 / Homeobox protein SIX6 / Q9QZ28* / O95475* / SIX homeobox 6* / sine oculis-related homeobox 6*ENSGALG0000002035968
SIX2 / homeobox protein SIX2 / Q62232* / Q9NPC8* / SIX homeobox 2*ENSGALG0000002330346
SIX1 / SIX homeobox 1 / Q15475* / Q62231* / Homeobox protein SIX1 *ENSGALG0000002940145
SIX4 / SIX homeobox 4 / Q61321* / Q9UIU6* / Homeobox protein SIX4 *ENSGALG0000001738940


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR031701  Homeobox protein SIX1, N-terminal SD domain
 IPR032949  Homeobox protein SIX3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation IEA
 biological_processGO:0001654 eye development IEA
 biological_processGO:0002070 epithelial cell maturation IEA
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0003404 optic vesicle morphogenesis IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009946 proximal/distal axis specification IEA
 biological_processGO:0014016 neuroblast differentiation IEA
 biological_processGO:0021536 diencephalon development IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0021797 forebrain anterior/posterior pattern specification IEA
 biological_processGO:0021798 forebrain dorsal/ventral pattern formation IEA
 biological_processGO:0021846 cell proliferation in forebrain IEA
 biological_processGO:0021978 telencephalon regionalization IEA
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048512 circadian behavior IEA
 biological_processGO:0060235 lens induction in camera-type eye IEA
 biological_processGO:0061074 regulation of neural retina development IEA
 biological_processGO:0070306 lens fiber cell differentiation IEA
 biological_processGO:0097402 neuroblast migration IEA
 biological_processGO:1901987 regulation of cell cycle phase transition IEA
 biological_processGO:1902692 regulation of neuroblast proliferation IEA
 biological_processGO:1902742 apoptotic process involved in development IEA
 biological_processGO:1990086 lens fiber cell apoptotic process IEA
 biological_processGO:2000177 regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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