ENSDARG00000075560


Danio rerio

Features
Gene ID: ENSDARG00000075560
  
Biological name :kmt2cb
  
Synonyms : kmt2cb / lysine (K)-specific methyltransferase 2Cb
  
Possible biological names infered from orthology : KMT2C / lysine methyltransferase 2C / Q8NEZ4
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 12847602
Gene end: 13037544
  
Corresponding Affymetrix probe sets: Dr.6241.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000122949
Ensembl peptide - ENSDARP00000149300
NCBI entrez gene - 568162     See in Manteia.
RefSeq - XM_005163297
swissprot - F1R598
ZFIN ID - ZDB-GENE-070705-340
Ensembl - ENSDARG00000075560
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032600Gallus gallus
 ENSGALG00000043738Gallus gallus
 KMT2CENSG00000055609Homo sapiens
 Kmt2cENSMUSG00000038056Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kmt2ca / lysine (K)-specific methyltransferase 2Ca / KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*ENSDARG0000007931248
kmt2d / lysine (K)-specific methyltransferase 2D / O14686* / Q6PDK2* / lysine methyltransferase 2D* / Histone-lysine N-methyltransferase 2D *ENSDARG0000003706018
kmt2a / lysine (K)-specific methyltransferase 2A / P55200* / Q03164* / lysine methyltransferase 2A* / Mus musculus lysine (K)-specific methyltransferase 2A (Kmt2a), transcript variant 1, mRNA.*ENSDARG000000045379
kmt2bb / lysine (K)-specific methyltransferase 2Bb / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *ENSDARG000000606978
kmt2ba / lysine (K)-specific methyltransferase 2Ba / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *ENSDARG000000629628
setd1ba / SET domain containing 1B, a / Q9UPS6* / SETD1B* / Q8CFT2* / SET domain containing 1B* / Histone-lysine N-methyltransferase SETD1B *ENSDARG000000608476
setd1a / SET domain containing 1A / O15047* / AC149222.1*ENSDARG000000600305
setd1bb / SET domain containing 1B, bENSDARG000000772443


Protein motifs (from Interpro)
Interpro ID Name
 IPR000637  HMG-I/HMG-Y, DNA-binding, conserved site
 IPR001214  SET domain
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR003616  Post-SET domain
 IPR003888  FY-rich, N-terminal
 IPR003889  FY-rich, C-terminal
 IPR009071  High mobility group box domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019787  Zinc finger, PHD-finger
 IPR034732  Extended PHD (ePHD) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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