Manteia

ENSDARG00000079312

Danio rerio

Features

Gene ID:	ENSDARG00000079312

Biological name :	kmt2ca

Synonyms :	kmt2ca / lysine (K)-specific methyltransferase 2Ca

Possible biological names infered from orthology :	KMT2C / lysine methyltransferase 2C / Q8NEZ4

Species:	Danio rerio

Chr. number:	24
Strand:	1
Band:
Gene start:	7336411
Gene end:	7549610

Corresponding Affymetrix probe sets:	Dr.14840.1.A1_at (Zebrafish Array) Dr.18611.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000149491 Ensembl peptide - ENSDARP00000153614 Ensembl peptide - ENSDARP00000115827 Ensembl peptide - ENSDARP00000121981 Ensembl peptide - ENSDARP00000137245 Ensembl peptide - ENSDARP00000148915 NCBI entrez gene - 560793 See in Manteia. RefSeq - XM_005162547 swissprot - A0A0R4IM21 swissprot - F1Q6F2 swissprot - F1R5P1 ZFIN ID - ZDB-GENE-080520-3 Ensembl - ENSDARG00000079312

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
kmt2cb / lysine (K)-specific methyltransferase 2Cb / KMT2C* / Q8NEZ4* / lysine methyltransferase 2C*	ENSDARG00000075560	48
kmt2d / lysine (K)-specific methyltransferase 2D / O14686* / Q6PDK2* / lysine methyltransferase 2D* / Histone-lysine N-methyltransferase 2D *	ENSDARG00000037060	19
kmt2a / lysine (K)-specific methyltransferase 2A / P55200* / Q03164* / lysine methyltransferase 2A* / Mus musculus lysine (K)-specific methyltransferase 2A (Kmt2a), transcript variant 1, mRNA.*	ENSDARG00000004537	9
kmt2bb / lysine (K)-specific methyltransferase 2Bb / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *	ENSDARG00000060697	9
kmt2ba / lysine (K)-specific methyltransferase 2Ba / KMT2B* / O08550* / Q9UMN6* / lysine methyltransferase 2B* / Histone-lysine N-methyltransferase 2B *	ENSDARG00000062962	8
setd1a / SET domain containing 1A / O15047* / AC149222.1*	ENSDARG00000060030	6
setd1ba / SET domain containing 1B, a / Q9UPS6* / SETD1B* / Q8CFT2* / SET domain containing 1B* / Histone-lysine N-methyltransferase SETD1B *	ENSDARG00000060847	6
setd1bb / SET domain containing 1B, b	ENSDARG00000077244	3

Protein motifs (from Interpro)

Interpro ID	Name
IPR001214	SET domain
IPR001841	Zinc finger, RING-type
IPR001965	Zinc finger, PHD-type
IPR003616	Post-SET domain
IPR003888	FY-rich, N-terminal
IPR003889	FY-rich, C-terminal
IPR009071	High mobility group box domain
IPR011011	Zinc finger, FYVE/PHD-type
IPR013083	Zinc finger, RING/FYVE/PHD-type
IPR015943	WD40/YVTN repeat-like-containing domain superfamily
IPR019787	Zinc finger, PHD-finger
IPR034732	Extended PHD (ePHD) domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0032259	methylation	IEA
biological_process	GO:0034968	histone lysine methylation	IEA
biological_process	GO:0051568	histone H3-K4 methylation	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0044666	MLL3/4 complex	IEA
molecular_function	GO:0008168	methyltransferase activity	IEA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0018024	histone-lysine N-methyltransferase activity	IEA
molecular_function	GO:0042800	histone methyltransferase activity (H3-K4 specific)	IEA
molecular_function	GO:0046872	metal ion binding	IEA

Pathways (from Reactome)

Pathway description

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000054	pericardium	pericardium edematous , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr