ENSDARG00000075932


Danio rerio
mhcclassiiantigenalphachainn-terminalimmunoglobulincompleximmunoglobulin-likeproteinpresentationmembranemajorhistocompatibilityconservedsitec-setdomainclassesii-likerecognitionfoldbetaimmuneresponseprocessingintegralcomponent

Features
Gene ID: ENSDARG00000075932
  
Biological name :si:ch73-211l2.3
  
Synonyms : si:ch73-211l2.3
  
Possible biological names infered from orthology : H2-Aa / H-2 class II histocompatibility antigen, A-B alpha chain / H2-Oa / HLA-DOA / HLA-DPA1 / HLA-DQA1 / HLA-DQA2 / HLA-DRA / major histocompatibility complex, class II, DO alpha / major histocompatibility complex, class II, DP alpha 1 / major histocompatibility complex, class II, DQ alpha 1 / major histocompatibility complex, class II, DQ alpha 2 / major histocompatibility complex, class II, DR alpha / P01903 / P01906 / P01909 / P06340 / P14434 / P20036
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 44475793
Gene end: 44480456
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000010619
Ensembl peptide - ENSDARP00000145272
NCBI entrez gene - 571282     See in Manteia.
swissprot - M9MM93
ZFIN ID - ZDB-GENE-081105-52
Ensembl - ENSDARG00000075932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P01903ENSG00000204287Homo sapiens
 P01906ENSG00000237541Homo sapiens
 P01909ENSG00000196735Homo sapiens
 P06340ENSG00000204252Homo sapiens
 P20036ENSG00000231389Homo sapiens
 H2-AaENSMUSG00000036594Mus musculus
 H2-OaENSMUSG00000024334Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:busm1-266f07.2 / H2-Aa* / H2-Oa* / P20036* / P06340* / P14434* / P01903* / P01906* / P01909* / HLA-DRA* / HLA-DOA* / HLA-DPA1* / HLA-DQA1* / HLA-DQA2* / major histocompatibility complex,...ENSDARG0000003174550
si:busm1-194e12.11 / H2-Aa* / H2-Oa* / P20036* / P06340* / P14434* / P01903* / P01906* / P01909* / HLA-DRA* / HLA-DOA* / HLA-DPA1* / HLA-DQA1* / HLA-DQA2* / major histocompatibility complex...ENSDARG0000010371649
si:busm1-194e12.8 / P20036* / P06340* / P01903* / P01909* / P01906* / HLA-DRA* / HLA-DOA* / HLA-DPA1* / HLA-DQA1* / HLA-DQA2* / major histocompatibility complex, class II, DR alpha* / major...ENSDARG0000010370247
si:zfos-367g9.1 / H2-Aa* / H2-Oa* / P20036* / P06340* / P14434* / P01903* / P01906* / P01909* / HLA-DRA* / HLA-DOA* / HLA-DPA1* / HLA-DQA1* / HLA-DQA2* / major histocompatibility complex, c...ENSDARG0000007481646
CT583723.2 / P20036* / P01903* / P01906* / P01909* / P06340* / HLA-DRA* / HLA-DOA* / HLA-DQA1* / HLA-DQA2* / HLA-DPA1* / major histocompatibility complex, class II, DR alpha* / major histoc...ENSDARG0000011656546
si:zfos-2070c2.1 / si:busm1-160c18.6 / H2-Aa* / H2-Oa* / P06340* / P20036* / P01903* / P01906* / P01909* / P14434* / HLA-DRA* / HLA-DOA* / HLA-DQA2* / HLA-DPA1* / HLA-DQA1* / major histocom...ENSDARG0000007020645
CU914776.2 / P20036* / P01903* / P01906* / P01909* / P06340* / HLA-DRA* / HLA-DOA* / HLA-DQA1* / HLA-DQA2* / HLA-DPA1* / major histocompatibility complex, class II, DR alpha* / major histoc...ENSDARG0000011460139
zgc:123107 / H2-Aa* / H2-Oa* / P20036* / P06340* / P14434* / P01903* / P01906* / P01909* / HLA-DRA* / HLA-DOA* / HLA-DPA1* / HLA-DQA1* / HLA-DQA2* / major histocompatibility complex, class ...ENSDARG0000010167531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001003  MHC class II, alpha chain, N-terminal
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR013783  Immunoglobulin-like fold
 IPR014745  MHC class II, alpha/beta chain, N-terminal


Gene Ontology (GO)
immune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseantigen processing and presentationimmune responseimmune responseantigen processing and presentationantigen processing and presentation
membranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranecellprotein-containing complexmembranemembranecellcellprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response IEA
 biological_processGO:0019882 antigen processing and presentation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042613 MHC class II protein complex IEA


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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