ENSDARG00000075949


Danio rerio

Features
Gene ID: ENSDARG00000075949
  
Biological name :prkd1
  
Synonyms : prkd1 / protein kinase D1
  
Possible biological names infered from orthology : Q15139 / Q62101
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 28882977
Gene end: 28969194
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000129639
Ensembl peptide - ENSDARP00000098837
NCBI entrez gene - 557123     See in Manteia.
RefSeq - XM_005158816
swissprot - X1WHC7
swissprot - E7FA73
ZFIN ID - ZDB-GENE-080131-1
Ensembl - ENSDARG00000075949
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKD1ENSGALG00000009900Gallus gallus
 PRKD1ENSG00000184304Homo sapiens
 Prkd1ENSMUSG00000002688Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkd3 / protein kinase D3 / O94806* / Q8K1Y2*ENSDARG0000007996768
prkd2 / protein kinase D2 / Q8BZ03* / Q9BZL6*ENSDARG0000010467644
zgc:175248ENSDARG0000010415342
lrrk2 / leucine-rich repeat kinase 2 / Q5S006* / Q5S007* / Leucine-rich repeat serine/threonine-protein kinase 2 *ENSDARG0000000616919
lrrk1 / leucine-rich repeat kinase 1 / Q38SD2* / Q3UHC2* / Leucine-rich repeat serine/threonine-protein kinase 1 *ENSDARG0000000739813
FO704748.1 / PRKD2* / Q9BZL6* / protein kinase D2*ENSDARG0000008701812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR015727  Protein kinase C mu-related
 IPR017441  Protein kinase, ATP binding site
 IPR020454  Diacylglycerol/phorbol-ester binding


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045765 regulation of angiogenesis IMP
 biological_processGO:0089700 protein kinase D signaling IBA
 biological_processGO:1901490 regulation of lymphangiogenesis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004697 protein kinase C activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001057 intersegmental vein intersegmental vein malformed , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
Show

 ZFA:0005110 thoracic duct thoracic duct absent , abnormal
Show

 ZFA:0005605 lymphangioblast cord lymphangioblast cord malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000024325 col4a3bpa / collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a / Q9EQG9* / Q9Y5P4* / COL4A3BP* / collagen type IV alpha 3 binding protein*  / reaction






 

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