ENSDARG00000076317


Danio rerio

Features
Gene ID: ENSDARG00000076317
  
Biological name :wu:fb72h05
  
Synonyms : plod3 / wu:fb72h05
  
Possible biological names infered from orthology : O60568 / procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 / Q9R0E1
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 44843860
Gene end: 44879214
  
Corresponding Affymetrix probe sets: Dr.330.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000080199
Ensembl peptide - ENSDARP00000123997
Ensembl peptide - ENSDARP00000124969
NCBI entrez gene - 556077     See in Manteia.
RefSeq - NM_001044343
RefSeq Peptide - NP_001037808
swissprot - F8W3X8
swissprot - A3KNH4
swissprot - F8W5U8
ZFIN ID - ZDB-GENE-021031-4
ZFIN ID - ZDB-GENE-030131-1486
Ensembl - ENSDARG00000076317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLOD3ENSG00000106397Homo sapiens
 Plod3ENSMUSG00000004846Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
plod2 / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 / O00469* / Q9R0B9*ENSDARG0000001182158
plod1a / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a / PLOD1* / Q9R0E2* / Q02809* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 1*ENSDARG0000005974658
colgalt2 / collagen beta(1-O)galactosyltransferase 2 / Q6NVG7* / Q8IYK4* / Procollagen galactosyltransferase 2 *ENSDARG0000001467014
si:ch211-13f8.2 / Q8IYK4* / Q6NVG7* / COLGALT2* / Procollagen galactosyltransferase 2 * / collagen beta(1-O)galactosyltransferase 2*ENSDARG0000007829914
cercam / cerebral endothelial cell adhesion molecule / A3KGW5* / Q5T4B2* / Inactive glycosyltransferase 25 family member 3 *ENSDARG0000007904914
A5PMF6 / COLGALT1 / si:ch211-114l13.7 / Q8K297* / Q8NBJ5* / Procollagen galactosyltransferase 1 * / collagen beta(1-O)galactosyltransferase 1*ENSDARG0000005827013
colgalt1 / collagen beta(1-O)galactosyltransferase 1 / Q8K297* / Q8NBJ5* / Procollagen galactosyltransferase 1 *ENSDARG0000007397413


Protein motifs (from Interpro)
Interpro ID Name
 IPR001006  Procollagen-lysine 5-dioxygenase
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit
 IPR029044  Nucleotide-diphospho-sugar transferases


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008475 procollagen-lysine 5-dioxygenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000029 hindbrain hindbrain quality , abnormal
hindbrain morphology , abnormal
Show

 ZFA:0000135 notochord notochord degenerate , abnormal
notochord undulate , abnormal
Show

 ZFA:0000155 somite somite quality , abnormal
somite morphology , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature contractility , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism movement behavioral quality , abnormal
Show

 ZFA:0001115 trunk trunk motor neuron axon guidance process quality , abnormal
Show

 ZFA:0005179 MiP motor neuron MiP motor neuron axon absent , abnormal
MiP motor neuron axon mislocalised , abnormal
Show

 ZFA:0005180 RoP motor neuron RoP motor neuron axon mislocalised , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell lacks parts or has fewer parts of type neural crest cell filopodium, abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron axon decreased length , abnormal
CaP motoneuron axon mislocalised , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000011821 plod2 / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 / O00469* / Q9R0B9*  / reaction
 ENSDARG00000059746 plod1a / procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a / PLOD1* / Q9R0E2* / Q02809* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 1*  / reaction
 ENSDARG00000076317 plod3 / wu:fb72h05 / O60568* / Q9R0E1* / procollagen-lysine,2-oxoglutarate 5-dioxygenase 3*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr