ENSDARG00000076318


Danio rerio

Features
Gene ID: ENSDARG00000076318
  
Biological name :atp6v1ab
  
Synonyms : atp6v1ab / ATPase H+ transporting V1 subunit Ab
  
Possible biological names infered from orthology : ATP6V1A / ATPase H+ transporting V1 subunit A / Mus musculus ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a), transcript variant 2, mRNA. / P38606 / P50516
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 21154120
Gene end: 21172122
  
Corresponding Affymetrix probe sets: Dr.2855.1.A1_a_at (Zebrafish Array)   Dr.2855.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000128988
NCBI entrez gene - 337583     See in Manteia.
RefSeq - XM_002666640
RefSeq - XM_021470316
swissprot - E7FCD8
ZFIN ID - ZDB-GENE-030131-9529
Ensembl - ENSDARG00000076318
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP6V1AENSGALG00000014800Gallus gallus
 P38606ENSG00000114573Homo sapiens
 P50516ENSMUSG00000052459Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp6v1aa / ATPase H+ transporting V1 subunit Aa / P50516* / P38606* / ATP6V1A* / ATPase H+ transporting V1 subunit A* / Mus musculus ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a...ENSDARG0000003453497


Protein motifs (from Interpro)
Interpro ID Name
 IPR000194  ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
 IPR004100  ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
 IPR005725  ATPase, V1 complex, subunit A
 IPR020003  ATPase, alpha/beta subunit, nucleotide-binding domain, active site
 IPR022878  V-type ATP synthase catalytic alpha chain
 IPR024034  ATPase, F1/V1 complex, beta/alpha subunit, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031686  ATPsynthase alpha/beta subunit, N-terminal extension


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0046034 ATP metabolic process IEA
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0033180 proton-transporting V-type ATPase, V1 domain IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000076318 atp6v1ab / ATPase H+ transporting V1 subunit Ab / P50516* / P38606* / ATP6V1A* / ATPase H+ transporting V1 subunit A* / Mus musculus ATPase, H+ transporting, lysosomal V1 subunit A (Atp6v1a...  / complex






 

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