ENSDARG00000076439


Danio rerio

Features
Gene ID: ENSDARG00000076439
  
Biological name :ppp4cb
  
Synonyms : A9JRC7 / ppp4cb / protein phosphatase 4, catalytic subunit b
  
Possible biological names infered from orthology : P60510 / P97470 / PPP4C / protein phosphatase 4 catalytic subunit
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 3964351
Gene end: 3978342
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000103385
Ensembl peptide - ENSDARP00000124845
NCBI entrez gene - 562705     See in Manteia.
RefSeq - NM_001111168
RefSeq Peptide - NP_001104638
swissprot - F8W259
swissprot - A9JRC7
ZFIN ID - ZDB-GENE-080219-32
Ensembl - ENSDARG00000076439
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPP4CENSG00000149923Homo sapiens
 Ppp4cENSMUSG00000030697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppp4ca / A8WGP3 / protein phosphatase 4, catalytic subunit a / PPP4C* / P97470* / P60510* / protein phosphatase 4 catalytic subunit*ENSDARG0000007057096
ppp2ca / protein phosphatase 2, catalytic subunit, alpha isozymeENSDARG0000003022464
PPP2CA / zgc:56064 / P67775* / P63330* / protein phosphatase 2 catalytic subunit alpha* / Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform *ENSDARG0000005340464
ppp2cb / protein phosphatase 2, catalytic subunit, beta isozyme / P62715* / P62714* / protein phosphatase 2 catalytic subunit beta* / Serine/threonine-protein phosphatase 2A catalytic subun...ENSDARG0000009924164


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0030513 positive regulation of BMP signaling pathway IMP
 biological_processGO:0048264 determination of ventral identity IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Processing of DNA double-strand break ends


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
whole organism necrotic , abnormal
whole organism elongated , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026540 ppp4r2a / protein phosphatase 4, regulatory subunit 2a / PPP4R2* / Q9NY27* / protein phosphatase 4 regulatory subunit 2*  / complex
 ENSDARG00000053447 A1L1M4 / ppp4r2b / protein phosphatase 4, regulatory subunit 2b / PPP4R2* / Q9NY27* / protein phosphatase 4 regulatory subunit 2*  / complex
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction






 

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