ENSDARG00000099241


Danio rerio

Features
Gene ID: ENSDARG00000099241
  
Biological name :ppp2cb
  
Synonyms : ppp2cb / protein phosphatase 2, catalytic subunit, beta isozyme
  
Possible biological names infered from orthology : P62714 / P62715 / protein phosphatase 2 catalytic subunit beta / Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 7593185
Gene end: 7617748
  
Corresponding Affymetrix probe sets: Dr.5120.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000137035
Ensembl peptide - ENSDARP00000140225
Ensembl peptide - ENSDARP00000139999
NCBI entrez gene - 406582     See in Manteia.
swissprot - A8E583
swissprot - A0A0R4IV29
swissprot - Q803G3
ZFIN ID - ZDB-GENE-040426-2487
Ensembl - ENSDARG00000099241
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P48463ENSGALG00000010273Gallus gallus
 P62714ENSG00000104695Homo sapiens
 P62715ENSMUSG00000009630Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP2CA / zgc:56064 / P67775* / P63330* / protein phosphatase 2 catalytic subunit alpha* / Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform *ENSDARG0000005340496
ppp2ca / protein phosphatase 2, catalytic subunit, alpha isozymeENSDARG0000003022494
ppp4ca / A8WGP3 / protein phosphatase 4, catalytic subunit a / PPP4C* / P97470* / P60510* / protein phosphatase 4 catalytic subunit*ENSDARG0000007057064
ppp4cb / A9JRC7 / protein phosphatase 4, catalytic subunit b / PPP4C* / P97470* / P60510* / protein phosphatase 4 catalytic subunit*ENSDARG0000007643964


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR006186  Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000078308 spry2 / sprouty RTK signaling antagonist 2 / O43597* / Q9QXV8*  / complex
 ENSDARG00000038059 grb2b / growth factor receptor-bound protein 2b / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex
 ENSDARG00000105276 grb2a / growth factor receptor-bound protein 2a / GRB2* / Q60631* / P62993* / growth factor receptor bound protein 2*  / complex






 

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