ENSDARG00000076763


Danio rerio
sp2factorrnapolymeraseiiorganismbindingzincfingerch-typespregulationmulticellulargrowthnucleusactivitysequence-specificdnanucleicacidsomitewholeheadpost-ventregion

Features
Gene ID: ENSDARG00000076763
  
Biological name :sp2
  
Synonyms : sp2 / sp2 transcription factor
  
Possible biological names infered from orthology : Q02086
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 11983465
Gene end: 12008001
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000098588
NCBI entrez gene - 556835     See in Manteia.
RefSeq - NM_001099982
RefSeq Peptide - NP_001093452
swissprot - F1Q4L6
ZFIN ID - ZDB-GENE-080410-1
Ensembl - ENSDARG00000076763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SP2ENSGALG00000000233Gallus gallus
 SP2ENSG00000167182Homo sapiens
 Sp2ENSMUSG00000018678Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sp4 / sp4 transcription factor / Q02446*ENSDARG0000000518631
sp3a / sp3a transcription factor / SP3* / Q02447* / O70494* / Sp3 transcription factor* / Transcription factor Sp3 *ENSDARG0000000154925
sp1 / sp1 transcription factor / O89090* / P08047* / Transcription factor Sp1 *ENSDARG0000008834724
sp3b / Sp3b transcription factor / SP3* / Q02447* / O70494* / Sp3 transcription factor* / Transcription factor Sp3 *ENSDARG0000000781223
sp8a / sp8 transcription factor a / SP8* / Q8IXZ3* / Q8BMJ8* / Sp8 transcription factor* / Transcription factor Sp8 *ENSDARG0000001187019
sp8b / Q6P0J3 / sp8 transcription factor bENSDARG0000005666619
sp5a / Sp5 transcription factor a / SP5* / Q9JHX2* / Q6BEB4* / Sp5 transcription factor* / Transcription factor Sp5 *ENSDARG0000007657118
sp9 / Q6NW96 / sp9 transcription factor / Q64HY3* / P0CG40* / Transcription factor Sp9 *ENSDARG0000009937418
FO704755.1ENSDARG0000000584617
sp7 / Sp7 transcription factor / Q8TDD2* / Q8VI67* / Mus musculus Sp7 transcription factor 7 (Sp7), transcript variant 2, mRNA.*ENSDARG0000001951616
klf11b / Kruppel-like factor 11b / KLF11* / Q8K1S5* / O14901* / Kruppel like factor 11* / Krueppel-like factor 11 *ENSDARG0000001379415
sp5l / Sp5 transcription factor-like / SP5* / Q6BEB4* / Sp5 transcription factor*ENSDARG0000011586815
klf11a / Kruppel-like factor 11a / KLF11* / Q8K1S5* / O14901* / Kruppel like factor 11* / Krueppel-like factor 11 *ENSDARG0000003084413
sp6 / Sp6 transcription factor / Q3SY56* / Q9ESX2* / trans-acting transcription factor 6*ENSDARG0000009988012
klf13 / Kruppel-like factor 13 / Q9JJZ6* / Q9Y2Y9* / Krueppel-like factor 13 *ENSDARG0000006136811
klf9 / Kruppel-like factor 9 / Q13886*ENSDARG0000006819410
zgc:153115ENSDARG0000006934210


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR030451  Transcription factor Sp2


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processdevelopmental growthnitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processdevelopmental growthdevelopmental growth
DNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activityDNA-binding transcription factor activityorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0035264 multicellular organism growth IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite malformed , abnormal
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 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
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 ZFA:0001114 head head malformed , abnormal
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 ZFA:0001117 post-vent region post-vent region malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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