ENSDARG00000077053


Danio rerio

Features
Gene ID: ENSDARG00000077053
  
Biological name :ppfia3
  
Synonyms : ppfia3 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
  
Possible biological names infered from orthology : O75145 / P60469 / PTPRF interacting protein alpha 3
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 30044011
Gene end: 30123113
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127938
Ensembl peptide - ENSDARP00000147975
Ensembl peptide - ENSDARP00000098951
NCBI entrez gene - 567230     See in Manteia.
RefSeq - XM_003198113
swissprot - E7F905
swissprot - X1WCJ5
ZFIN ID - ZDB-GENE-100311-3
Ensembl - ENSDARG00000077053
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O75145ENSG00000177380Homo sapiens
 P60469ENSMUSG00000003863Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppfia2 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 / O75334* / PTPRF interacting protein alpha 2*ENSDARG0000001300061
ppfia4 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 / O75335* / PTPRF interacting protein alpha 4*ENSDARG0000005320558
ppfia1 / protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 / Q13136* / PTPRF interacting protein alpha 1*ENSDARG0000009867427
kazna / A9C3W3 / kazrin, periplakin interacting protein a / KAZN* / Q69ZS8* / Q674X7* / Kazrin * / kazrin, periplakin interacting protein*ENSDARG0000007692316
ppfibp1b / PTPRF interacting protein, binding protein 1b (liprin beta 1) / Q86W92* / PPFIBP1* / PPFIA binding protein 1*ENSDARG0000010005716
ppfibp1a / PTPRF interacting protein, binding protein 1a (liprin beta 1) / Q86W92* / Q8C8U0* / PPFIBP1* / PPFIA binding protein 1* / PTPRF interacting protein, binding protein 1 (liprin beta 1)*ENSDARG0000004574915
ppfibp2a / PTPRF interacting protein, binding protein 2a (liprin beta 2) / O35711* / Q8ND30* / PPFIBP2* / PPFIA binding protein 2* / PTPRF interacting protein, binding protein 2 (liprin beta 2)*ENSDARG0000006197714
kaznb / kazrin, periplakin interacting protein b / KAZN* / Q69ZS8* / Q674X7* / Kazrin * / kazrin, periplakin interacting protein*ENSDARG000000066018
ppfibp2b / PTPRF interacting protein, binding protein 2b (liprin beta 2) / O35711* / Q8ND30* / PPFIBP2* / PPFIA binding protein 2* / PTPRF interacting protein, binding protein 2 (liprin beta 2)*ENSDARG000000291684


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR029515  LAR-interacting protein, Liprin
 IPR030440  Liprin-alpha-3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001944 vasculature development IMP
 biological_processGO:0007269 neurotransmitter secretion IEA
 cellular_componentGO:0048786 presynaptic active zone IEA


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Receptor-type tyrosine-protein phosphatases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta anatomical margin shape , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000155 somite somite shape , abnormal
somite obtuse angle to somite , abnormal
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 ZFA:0000471 atrium atrium dilated , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein anatomical margin shape , abnormal
Show

 ZFA:0001115 trunk trunk decreased distribution , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000005754 ptprfb / A4IFW2 / protein tyrosine phosphatase, receptor type, f, b / PTPRF* / P10586* / A2A8L5* / Receptor-type tyrosine-protein phosphatase F * / protein tyrosine phosphatase, receptor type F*  / complex / reaction






 

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