ENSDARG00000089334


Danio rerio

Features
Gene ID: ENSDARG00000089334
  
Biological name :ednrba
  
Synonyms : ednrba / endothelin receptor Ba
  
Possible biological names infered from orthology : EDNRB / endothelin receptor type B / P24530 / P48302
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 28624186
Gene end: 28629471
  
Corresponding Affymetrix probe sets: Dr.10456.1.S1_at (Zebrafish Array)   NM_131197_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000111210
NCBI entrez gene - 30442     See in Manteia.
RefSeq - NM_131197
RefSeq Peptide - NP_571272
swissprot - Q9DGM2
ZFIN ID - ZDB-GENE-980526-16
Ensembl - ENSDARG00000089334
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EDNRBENSGALG00000016912Gallus gallus
 EDNRBENSG00000136160Homo sapiens
 EdnrbENSMUSG00000022122Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ednrbb / endothelin receptor type Bb / EDNRB* / P24530* / P48302* / endothelin receptor type B*ENSDARG0000005349854
ednraa / endothelin receptor type Aa / EDNRA* / P25101* / Q61614* / Endothelin-1 receptor * / endothelin receptor type A*ENSDARG0000001187653
ednrab / endothelin receptor type Ab / EDNRA* / P25101* / Q61614* / Endothelin-1 receptor * / endothelin receptor type A*ENSDARG0000006226250
grpr / gastrin-releasing peptide receptor / P21729* / P30550*ENSDARG0000005662025
nmbr / neuromedin B receptor / O54799* / P28336*ENSDARG0000005415223
gpr37l1a / G protein-coupled receptor 37 like 1a / Q99JG2* / O60883* / GPR37L1* / G protein-coupled receptor 37 like 1*ENSDARG0000000607922
gpr37l1b / G protein-coupled receptor 37 like 1b / Q99JG2* / O60883* / GPR37L1* / G protein-coupled receptor 37 like 1*ENSDARG0000005677422
gpr37b / G protein-coupled receptor 37b / GPR37* / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*ENSDARG0000003329621
gpr37a / G protein-coupled receptor 37a / GPR37* / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*ENSDARG0000007456321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000499  Endothelin receptor family
 IPR001112  Endothelin receptor B
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048070 regulation of developmental pigmentation IMP
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0050935 iridophore differentiation IMP
 biological_processGO:0086100 endothelin receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004962 endothelin receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye has fewer parts of type iridophore , abnormal
Show

 ZFA:0000277 scale scale melanocyte increased amount , abnormal
scale iridophore increased amount , abnormal
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 ZFA:0001058 caudal fin caudal fin has fewer parts of type iridophore , abnormal
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 ZFA:0001115 trunk trunk has fewer parts of type melanophore stripe , abnormal
trunk dermis lacks all parts of type iridophore , abnormal
trunk melanophore stripe malformed , abnormal
trunk melanophore stripe has fewer parts of type melanocyte , abnormal
trunk dermis has fewer parts of type iridophore , abnormal
trunk dermis has fewer parts of type melanocyte , abnormal
trunk melanocyte mislocalised , abnormal
trunk iridophore mislocalised , abnormal
trunk melanocyte decreased amount , abnormal
trunk iridophore decreased amount , abnormal
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 ZFA:0001162 anal fin anal fin has fewer parts of type iridophore , abnormal
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 ZFA:0001463 melanophore stripe melanophore stripe lacks parts or has fewer parts of type melanocyte , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
pigment cell irregular spatial pattern , abnormal
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 ZFA:0009091 melanocyte melanocyte irregular spatial pattern , abnormal
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 ZFA:0009198 xanthophore xanthophore spatial pattern , abnormal
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 ZFA:0009199 iridophore iridophore irregular spatial pattern , abnormal
iridophore decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070578 edn2 / endothelin 2 / P20800* / P22389*  / complex / reaction
 ENSDARG00000086669 edn3b / endothelin 3b / EDN3* / P14138* / P48299* / endothelin 3*  / complex / reaction






 

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