ENSGALG00000016912


Gallus gallus

Features
Gene ID: ENSGALG00000016912
  
Biological name :EDNRB
  
Synonyms : EDNRB / endothelin receptor type B
  
Possible biological names infered from orthology : P24530 / P48302
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 153918344
Gene end: 153932319
  
Corresponding Affymetrix probe sets: Gga.10829.1.S1_s_at (Chicken Array)   Gga.2673.1.S1_at (Chicken Array)   Gga.3306.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048276
Ensembl peptide - ENSGALP00000035729
NCBI entrez gene - 408082     See in Manteia.
RefSeq - NM_001001127
RefSeq Peptide - NP_001001127
swissprot - F1NAJ4
swissprot - A0A1D5P6F1
Ensembl - ENSGALG00000016912
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ednrbaENSDARG00000089334Danio rerio
 ednrbbENSDARG00000053498Danio rerio
 EDNRBENSG00000136160Homo sapiens
 EdnrbENSMUSG00000022122Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EDNRB2 / endothelin receptor B subtype 2 precursor ENSGALG0000000746661
EDNRA / endothelin receptor type A / P25101* / Q61614* / Endothelin-1 receptor *ENSGALG0000001001353
BRS3 / bombesin receptor subtype 3 / O54798* / P32247*ENSGALG0000000640624
GRPR / gastrin-releasing peptide receptor / P21729* / P30550*ENSGALG0000002796024
NMBR / neuromedin B receptor / O54799* / P28336*ENSGALG0000001381323
GPR37L1 / G protein-coupled receptor 37 like 1 / O60883* / Q99JG2*ENSGALG0000000060722
GPR37 / prosaposin receptor GPR37 precursor / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*ENSGALG0000004095421


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000499  Endothelin receptor family
 IPR001112  Endothelin receptor B
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0006885 regulation of pH IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007422 peripheral nervous system development IEA
 biological_processGO:0007497 posterior midgut development IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0014043 negative regulation of neuron maturation IEA
 biological_processGO:0014826 vein smooth muscle contraction IEA
 biological_processGO:0019722 calcium-mediated signaling IEA
 biological_processGO:0030318 melanocyte differentiation IEA
 biological_processGO:0032269 negative regulation of cellular protein metabolic process IEA
 biological_processGO:0035645 enteric smooth muscle cell differentiation IEA
 biological_processGO:0042310 vasoconstriction IEA
 biological_processGO:0043473 pigmentation IEA
 biological_processGO:0048066 developmental pigmentation IEA
 biological_processGO:0048246 macrophage chemotaxis IEA
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0086100 endothelin receptor signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004962 endothelin receptor activity IEA
 molecular_functionGO:0017046 peptide hormone binding IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000667 EDN2 / endothelin 2 / P20800* / P22389*  / complex / reaction
 ENSGALG00000012735 EDN1 / endothelin 1 / P05305* / P22387* / Endothelin-1 Big endothelin-1*  / complex / reaction






 

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