ENSDARG00000096355


Danio rerio

Features
Gene ID: ENSDARG00000096355
  
Biological name :ighv1-4
  
Synonyms : ighv1-4 / immunoglobulin heavy variable 1-4
  
Possible biological names infered from orthology : Igha / IGHA1 / IGHA2 / IGHE / IGHG1 / IGHG2 / Ighg2b / Ighg2c / IGHG3 / IGHG4 / IGHM / immunoglobulin heavy constant alpha 1 / immunoglobulin heavy constant alpha 2 (A2m marker) / immunoglobulin heavy constant epsilon / immunoglobulin heavy constant gamma 1 (G1m marker) / immunoglobulin heavy constant gamma 2 (G2m marker) / immunoglobulin heavy constant gamma 3 (G3m marker) / immunoglobulin heavy constant gamma 4 (G4m marker) / immunoglobulin heavy constant mu / P01854 / P01857 / P01859 / P01861 / P01871 / P01876 / P01877
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 33963247
Gene end: 34095221
  
Corresponding Affymetrix probe sets: Dr.6141.1.S1_a_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000132299
Ensembl peptide - ENSDARP00000140922
Ensembl peptide - ENSDARP00000125722
Ensembl peptide - ENSDARP00000126084
Ensembl peptide - ENSDARP00000126090
swissprot - A0A0R4IBJ4
swissprot - A0A0R4IW73
swissprot - I3IT31
swissprot - M9MMC8
swissprot - M9MMF7
ZFIN ID - ZDB-GENE-040514-1
Ensembl - ENSDARG00000096355
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IGHA1ENSG00000211895Homo sapiens
 IGHA2ENSG00000211890Homo sapiens
 IGHEENSG00000211891Homo sapiens
 IGHG1ENSG00000211896Homo sapiens
 IGHG2ENSG00000211893Homo sapiens
 IGHG3ENSG00000211897Homo sapiens
 IGHG4ENSG00000211892Homo sapiens
 IGHMENSG00000211899Homo sapiens
 IghaENSMUSG00000095079Mus musculus
 IgheENSMUSG00000087642Mus musculus
 Ighg1ENSMUSG00000076614Mus musculus
 Ighg2bENSMUSG00000076613Mus musculus
 Ighg2cENSMUSG00000076612Mus musculus
 Ighg3ENSMUSG00000076615Mus musculus
 IghmENSMUSG00000076617Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ighd / immunoglobulin heavy constant deltaENSDARG0000009624812


Protein motifs (from Interpro)
Interpro ID Name
 IPR003597  Immunoglobulin C1-set
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
Initial triggering of complement
Classical antibody-mediated complement activation
FCGR activation
Regulation of actin dynamics for phagocytic cup formation
Role of phospholipids in phagocytosis
Regulation of Complement cascade
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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