ENSDARG00000098745


Danio rerio

Features
Gene ID: ENSDARG00000098745
  
Biological name :tfec
  
Synonyms : tfec / transcription factor EC
  
Possible biological names infered from orthology : O14948 / Q9WTW4
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 6032640
Gene end: 6047236
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000139802
NCBI entrez gene - 556894     See in Manteia.
RefSeq - NM_001030105
RefSeq Peptide - NP_001025276
swissprot - A0A0R4IEC1
swissprot - A0A0R4IX50
ZFIN ID - ZDB-GENE-041210-21
Ensembl - ENSDARG00000098745
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TFECENSGALG00000040557Gallus gallus
 TFECENSG00000105967Homo sapiens
 TfecENSMUSG00000029553Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mitfa / microphthalmia-associated transcription factor a / MITF* / O75030* / Q08874* / melanogenesis associated transcription factor*ENSDARG0000000373243
tfe3a / transcription factor binding to IGHM enhancer 3a / TFE3* / Q64092* / P19532* / Transcription factor E3 * / transcription factor binding to IGHM enhancer 3*ENSDARG0000009890343
mitfb / microphthalmia-associated transcription factor b / MITF* / O75030* / melanogenesis associated transcription factor*ENSDARG0000003783342
tfe3b / transcription factor binding to IGHM enhancer 3b / TFE3* / Q64092* / P19532* / Transcription factor E3 * / transcription factor binding to IGHM enhancer 3*ENSDARG0000001945741
tfeb / transcription factor EB / P19484* / Q9R210*ENSDARG0000001079439


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR021802  MiT/TFE transcription factors, C-terminal
 IPR024101  Transcription factor EC
 IPR031867  MiT/TFE transcription factors, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0060216 definitive hemopoiesis IMP
 biological_processGO:0061484 hematopoietic stem cell homeostasis IMP
 biological_processGO:0071425 hematopoietic stem cell proliferation IMP
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased pigmentation , abnormal
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 ZFA:0001094 whole organism whole organism decreased life span , abnormal
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 ZFA:0009014 hematopoietic stem cell hematopoietic stem cell decreased amount , abnormal
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 ZFA:0009043 circulating cell circulating cell decreased amount , abnormal
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 ZFA:0009044 blood cell blood cell decreased amount , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
Show

 ZFA:0009325 erythroid lineage cell erythroid lineage cell decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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