ENSDARG00000099339


Danio rerio

Features
Gene ID: ENSDARG00000099339
  
Biological name :pacsin3
  
Synonyms : pacsin3 / protein kinase C and casein kinase substrate in neurons 3
  
Possible biological names infered from orthology : Protein kinase C and casein kinase II substrate protein 3 / Q99JB8 / Q9UKS6
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 54222156
Gene end: 54308069
  
Corresponding Affymetrix probe sets: Dr.8025.1.S1_at (Zebrafish Array)   Dr.8025.2.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131278
Ensembl peptide - ENSDARP00000140870
Ensembl peptide - ENSDARP00000138886
Ensembl peptide - ENSDARP00000138125
NCBI entrez gene - 393964     See in Manteia.
RefSeq - XM_005166594
swissprot - B0R118
swissprot - A0A0R4IUX9
swissprot - A0A0R4IUF8
swissprot - Q7ZUY8
ZFIN ID - ZDB-GENE-040426-984
Ensembl - ENSDARG00000099339
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PACSIN3ENSGALG00000008231Gallus gallus
 Q9UKS6ENSG00000165912Homo sapiens
 Q99JB8ENSMUSG00000027257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pacsin2 / protein kinase C and casein kinase substrate in neurons 2 / Q9UNF0* / Q9WVE8*ENSDARG0000007801452
Q4V920 / pacsin1b / protein kinase C and casein kinase substrate in neurons 1b / Q61644* / Q9BY11* / PACSIN1* / protein kinase C and casein kinase substrate in neurons 1* / Protein kinase C...ENSDARG0000004212850
pacsin1a / protein kinase C and casein kinase substrate in neurons 1a / Q61644* / Q9BY11* / PACSIN1* / protein kinase C and casein kinase substrate in neurons 1* / Protein kinase C and case...ENSDARG0000003286549
si:ch211-51c14.1ENSDARG0000005464538
zgc:91999ENSDARG0000010500132


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR028523  Protein kinase C and casein kinase substrate in neurons protein 3
 IPR031160  F-BAR domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0014028 notochord formation IMP
 biological_processGO:0030100 regulation of endocytosis IBA
 biological_processGO:0060034 notochord cell differentiation IMP
 biological_processGO:0097320 plasma membrane tubulation IEA
 cellular_componentGO:0005768 endosome IBA
 cellular_componentGO:0005886 plasma membrane IDA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000106 extension extension aplastic , abnormal
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 ZFA:0000135 notochord notochord coiled , abnormal
notochord malformed , abnormal
notochord poorly differentiated , abnormal
notochord vacuole increased amount , abnormal
notochord vacuole decreased size , abnormal
notochord increased width , abnormal
notochord undulate , abnormal
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 ZFA:0000155 somite somite increased width , abnormal
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 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region bent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000099339 pacsin3 / protein kinase C and casein kinase substrate in neurons 3 / Q99JB8* / Q9UKS6* / Protein kinase C and casein kinase II substrate protein 3 *  / complex






 

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