ENSDARG00000099517


Danio rerio

Features
Gene ID: ENSDARG00000099517
  
Biological name :adssl1
  
Synonyms : adenylosuccinate synthase like 1 / adssl1 / Q6NSN5
  
Possible biological names infered from orthology : adenylosuccinate synthetase like 1 / P28650 / Q8N142
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 1323699
Gene end: 1355790
  
Corresponding Affymetrix probe sets: Dr.6517.1.S1_at (Zebrafish Array)   NM_214820_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000136105
NCBI entrez gene - 407989     See in Manteia.
RefSeq - NM_214820
RefSeq Peptide - NP_999985
swissprot - A0A0R4ILL7
swissprot - Q6NSN5
ZFIN ID - ZDB-GENE-040516-18
Ensembl - ENSDARG00000099517
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADSSL1ENSGALG00000011618Gallus gallus
 ADSSL1ENSG00000185100Homo sapiens
 Adssl1ENSMUSG00000011148Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
adss / Q568F6 / adenylosuccinate synthase / P30520* / P46664* / adenylosuccinate synthetase, non muscle*ENSDARG0000000207173
adssl / adenylosuccinate synthase, likeENSDARG0000001239966


Protein motifs (from Interpro)
Interpro ID Name
 IPR001114  Adenylosuccinate synthetase
 IPR018220  Adenylosuccinate synthase, GTP-binding site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027509  Adenylosuccinate synthetase isozyme 1, chordates
 IPR033128  Adenylosuccinate synthase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006164 purine nucleotide biosynthetic process IEA
 biological_processGO:0006167 AMP biosynthetic process IEA
 biological_processGO:0044208 "de novo" AMP biosynthetic process IBA
 biological_processGO:0046040 IMP metabolic process IBA
 biological_processGO:0046716 muscle cell cellular homeostasis IMP
 biological_processGO:0048741 skeletal muscle fiber development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004019 adenylosuccinate synthase activity IBA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Purine ribonucleoside monophosphate biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001089 myoseptum myoseptum damaged , abnormal
myoseptum U-shaped , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0005145 muscle muscle refractivity , abnormal
muscle skeletal muscle myofibril disorganized , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle skeletal muscle myofibril morphology , abnormal
Show

 ZFA:0009115 skeletal muscle cell skeletal muscle cell apoptotic , abnormal
skeletal muscle cell apoptotic process increased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000099517 adssl1 / Q6NSN5 / adenylosuccinate synthase like 1 / Q8N142*  / complex






 

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