ENSDARG00000099755


Danio rerio

Features
Gene ID: ENSDARG00000099755
  
Biological name :pfklb
  
Synonyms : pfklb / phosphofructokinase, liver b
  
Possible biological names infered from orthology : ATP-dependent 6-phosphofructokinase, liver type / P12382 / P17858 / PFKL / phosphofructokinase, liver type
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 44910615
Gene end: 44931962
  
Corresponding Affymetrix probe sets: Dr.15295.1.A1_at (Zebrafish Array)   Dr.15295.2.A1_at (Zebrafish Array)   Dr.25806.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131945
NCBI entrez gene - 550259     See in Manteia.
swissprot - A0A0R4ID68
swissprot - A0A0R4ITP0
ZFIN ID - ZDB-GENE-050417-62
Ensembl - ENSDARG00000099755
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PFKLENSGALG00000006543Gallus gallus
 PFKLENSG00000141959Homo sapiens
 PfklENSMUSG00000020277Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pfkla / phosphofructokinase, liver a / PFKL* / P12382* / P17858* / phosphofructokinase, liver type* / ATP-dependent 6-phosphofructokinase, liver type *ENSDARG0000006050483
pfkmb / phosphofructokinase, muscle b / PFKM* / P47857* / P08237* / phosphofructokinase, muscle* / Mus musculus phosphofructokinase, muscle (Pfkm), transcript variant 4, mRNA.*ENSDARG0000006079766
pfkma / phosphofructokinase, muscle a / PFKM* / P47857* / P08237* / phosphofructokinase, muscle* / Mus musculus phosphofructokinase, muscle (Pfkm), transcript variant 4, mRNA.*ENSDARG0000001417965
pfkpa / phosphofructokinase, platelet a / PFKP* / Q01813* / Q9WUA3* / phosphofructokinase, platelet* / ATP-dependent 6-phosphofructokinase, platelet type *ENSDARG0000002800064
pfkpb / phosphofructokinase, platelet b / PFKP* / Q01813* / Q9WUA3* / phosphofructokinase, platelet* / ATP-dependent 6-phosphofructokinase, platelet type *ENSDARG0000001280163


Protein motifs (from Interpro)
Interpro ID Name
 IPR000023  Phosphofructokinase domain
 IPR009161  ATP-dependent 6-phosphofructokinase, eukaryotic-type
 IPR015912  Phosphofructokinase, conserved site
 IPR022953  ATP-dependent 6-phosphofructokinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006002 fructose 6-phosphate metabolic process IEA
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0061615 glycolytic process through fructose-6-phosphate IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003872 6-phosphofructokinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014179 pfkma / phosphofructokinase, muscle a / PFKM* / P47857* / P08237* / phosphofructokinase, muscle* / Mus musculus phosphofructokinase, muscle (Pfkm), transcript variant 4, mRNA.*  / complex
 ENSDARG00000060797 pfkmb / phosphofructokinase, muscle b / PFKM* / P47857* / P08237* / phosphofructokinase, muscle* / Mus musculus phosphofructokinase, muscle (Pfkm), transcript variant 4, mRNA.*  / complex
 ENSDARG00000060504 pfkla / phosphofructokinase, liver a / PFKL* / P12382* / P17858* / phosphofructokinase, liver type* / ATP-dependent 6-phosphofructokinase, liver type *  / complex
 ENSDARG00000099755 pfklb / phosphofructokinase, liver b / PFKL* / P17858* / phosphofructokinase, liver type*  / complex






 

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