ENSGALG00000006543


Gallus gallus

Features
Gene ID: ENSGALG00000006543
  
Biological name :PFKL
  
Synonyms : Gallus gallus phosphofructokinase, liver type (PFKL), mRNA. / PFKL
  
Possible biological names infered from orthology : ATP-dependent 6-phosphofructokinase, liver type / P12382 / P17858 / phosphofructokinase, liver type
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 4375703
Gene end: 4380667
  
Corresponding Affymetrix probe sets: Gga.2810.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050836
Ensembl peptide - ENSGALP00000040387
NCBI entrez gene - 769850     See in Manteia.
RefSeq - XM_001232620
RefSeq - NM_001318442
RefSeq Peptide - NP_001305371
swissprot - A0A1D5PDJ1
swissprot - F1NKB6
Ensembl - ENSGALG00000006543
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pfklaENSDARG00000060504Danio rerio
 pfklbENSDARG00000099755Danio rerio
 PFKLENSG00000141959Homo sapiens
 PfklENSMUSG00000020277Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PFKP / phosphofructokinase, platelet / Q01813* / Q9WUA3* / ATP-dependent 6-phosphofructokinase, platelet type *ENSGALG0000000693965


Protein motifs (from Interpro)
Interpro ID Name
 IPR000023  Phosphofructokinase domain
 IPR009161  ATP-dependent 6-phosphofructokinase, eukaryotic-type
 IPR015912  Phosphofructokinase, conserved site
 IPR022953  ATP-dependent 6-phosphofructokinase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006002 fructose 6-phosphate metabolic process IEA
 biological_processGO:0006096 glycolytic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030388 fructose 1,6-bisphosphate metabolic process IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0061615 glycolytic process through fructose-6-phosphate IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005945 6-phosphofructokinase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003872 6-phosphofructokinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070061 fructose binding IEA
 molecular_functionGO:0070095 fructose-6-phosphate binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Glycolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006939 PFKP / phosphofructokinase, platelet / Q01813* / Q9WUA3* / ATP-dependent 6-phosphofructokinase, platelet type *  / complex
 ENSGALG00000006543 PFKL / Gallus gallus phosphofructokinase, liver type (PFKL), mRNA. / P12382* / P17858* / phosphofructokinase, liver type* / ATP-dependent 6-phosphofructokinase, liver type *  / complex






 

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