ENSDARG00000100372


Danio rerio
activityaladdelta-aminolevulinicaciddehydratasebiosyntheticprocessaldolase-typetimbarrelactivesiteporphyrin-containingcompoundtetrapyrrolecatalyticporphobilinogensynthaselyasemetalionbindinghemebiosynthesisneutrophildegranulation

Features
Gene ID: ENSDARG00000100372
  
Biological name :alad
  
Synonyms : alad / aminolevulinate dehydratase
  
Possible biological names infered from orthology : Delta-aminolevulinic acid dehydratase / P10518 / P13716
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 54482325
Gene end: 54497319
  
Corresponding Affymetrix probe sets: Dr.13193.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000136768
Ensembl peptide - ENSDARP00000145269
swissprot - A0A0R4IPV1
ZFIN ID - ZDB-GENE-050417-123
Ensembl - ENSDARG00000100372
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALADENSGALG00000008865Gallus gallus
 ALADENSG00000148218Homo sapiens
 AladENSMUSG00000028393Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001731  Delta-aminolevulinic acid dehydratase
 IPR013785  Aldolase-type TIM barrel
 IPR030656  Delta-aminolevulinic acid dehydratase, active site


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processnitrogen compound metabolic processnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic processcellular metabolic processorganic substance metabolic processorganic substance metabolic process
lyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activityion bindinglyase activitylyase activityion bindingion binding
TypeGO IDTermEv.Code
 biological_processGO:0006779 porphyrin-containing compound biosynthetic process IEA
 biological_processGO:0033014 tetrapyrrole biosynthetic process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004655 porphobilinogen synthase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Heme biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000100372 alad / aminolevulinate dehydratase / P10518* / P13716* / Delta-aminolevulinic acid dehydratase *  / complex






 

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