ENSGALG00000008865


Gallus gallus
processALADbiosyntheticproteinactivitybindingdelta-aminolevulinicaciddehydratasehemeionaldolase-typetimbarrelactivesiteporphyrin-containingcompoundtetrapyrrolehomooligomerizationcellularresponseinterleukin-regulationproteasomalcataboliccatalyticporphobilinogensynthasezinclyase

Features
Gene ID: ENSGALG00000008865
  
Biological name :ALAD
  
Synonyms : ALAD / aminolevulinate dehydratase
  
Possible biological names infered from orthology : Delta-aminolevulinic acid dehydratase / P10518 / P13716
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 1938858
Gene end: 1947767
  
Corresponding Affymetrix probe sets: Gga.5250.1.S1_a_at (Chicken Array)   GgaAffx.22705.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014385
NCBI entrez gene - 417273     See in Manteia.
RefSeq - NM_001291406
RefSeq Peptide - NP_001278335
swissprot - F1NN49
Ensembl - ENSGALG00000008865
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aladENSDARG00000100372Danio rerio
 ALADENSG00000148218Homo sapiens
 AladENSMUSG00000028393Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001731  Delta-aminolevulinic acid dehydratase
 IPR013785  Aldolase-type TIM barrel
 IPR030656  Delta-aminolevulinic acid dehydratase, active site


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen compound metabolic processbiosynthetic processcellular metabolic processorganic substance metabolic processpigment metabolic processcellular component organizationcellular component biogenesisresponse to chemicalcellular response to stimuluscatabolic processprimary metabolic processnitrogen comnitrogen compound metabolic processbiosyntheticbiosynthetic processcellular metcellular metabolic processorganic subsorganic substance metabolic processpigment metapigment metabolic processcellular comcellular component organizationcellular comcellular component biogenesisresponse to response to chemicalcellular rescellular response to stimuluscatabolic prcatabolic processprimary metaprimary metabolic process
lyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activityion bindingprotein bindinglyase activitylyase activityion bindingion bindingprotein bindingprotein binding
TypeGO IDTermEv.Code
 biological_processGO:0006779 porphyrin-containing compound biosynthetic process IEA
 biological_processGO:0006783 heme biosynthetic process IEA
 biological_processGO:0033014 tetrapyrrole biosynthetic process IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0071353 cellular response to interleukin-4 IEA
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004655 porphobilinogen synthase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Heme biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008865 ALAD / aminolevulinate dehydratase / P10518* / P13716* / Delta-aminolevulinic acid dehydratase *  / complex






 

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