ENSDARG00000101293


Danio rerio

Features
Gene ID: ENSDARG00000101293
  
Biological name :PKN2 (1 of many)
  
Synonyms : PKN2 (1 of many) / zgc:153916
  
Possible biological names infered from orthology : PKN2 / protein kinase N2 / Q16513 / Q8BWW9 / Serine/threonine-protein kinase N2
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 25312387
Gene end: 25384792
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000147780
Ensembl peptide - ENSDARP00000150862
Ensembl peptide - ENSDARP00000133716
Ensembl peptide - ENSDARP00000141424
NCBI entrez gene - 567134     See in Manteia.
RefSeq - NM_001080032
RefSeq Peptide - NP_001073501
swissprot - A0A0R4IJB4
swissprot - Q08BD6
ZFIN ID - ZDB-GENE-061013-393
Ensembl - ENSDARG00000101293
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PKN2ENSGALG00000006237Gallus gallus
 PKN2ENSG00000065243Homo sapiens
 Pkn2ENSMUSG00000004591Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pkn2 / protein kinase N2 / Q16513*ENSDARG0000010198379
pkn1a / protein kinase N1a / PKN1* / Q16512* / P70268* / protein kinase N1* / Serine/threonine-protein kinase N1 *ENSDARG0000006018459
pkn1b / protein kinase N1b / PKN1* / Q16512* / protein kinase N1*ENSDARG0000006274856
pkn3 / protein kinase N3 / Q6P5Z2* / Q8K045* / Serine/threonine-protein kinase N3 *ENSDARG0000007958553


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011072  HR1 rho-binding domain
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017049 GTP-Rho binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate PKNs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018285 pdpk1b / 3-phosphoinositide dependent protein kinase 1b / PDPK1* / O15530* / Q9Z2A0* / 3-phosphoinositide dependent protein kinase 1*  / complex / reaction
 ENSDARG00000018328 rhocb / Q6DHE8 / ras homolog family member Cb / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *  / complex / reaction
 ENSDARG00000094673 rhoab / Q6DHM9 / ras homolog gene family, member Ab / RHOA* / Q9QUI0* / P61586* / ras homolog family member A*  / complex / reaction
 ENSDARG00000021309 rhoca / ras homolog family member Ca / RHOC* / Q62159* / P08134* / ras homolog family member C* / Rho-related GTP-binding protein RhoC *  / complex / reaction






 

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