ENSDARG00000103176


Danio rerio

Features
Gene ID: ENSDARG00000103176
  
Biological name :nr5a1a
  
Synonyms : nr5a1a / nuclear receptor subfamily 5, group A, member 1a
  
Possible biological names infered from orthology : NR5A1 / nuclear receptor subfamily 5 group A member 1 / P33242 / Q13285 / Steroidogenic factor 1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 52833443
Gene end: 52871056
  
Corresponding Affymetrix probe sets: Dr.19909.1.S1_at (Zebrafish Array)   NM_131794_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000130433
Ensembl peptide - ENSDARP00000140514
Ensembl peptide - ENSDARP00000135759
NCBI entrez gene - 83916     See in Manteia.
RefSeq - NM_131794
RefSeq Peptide - NP_571869
swissprot - A0A0R4ITX5
swissprot - A0A0R4IN39
swissprot - F1QJG0
ZFIN ID - ZDB-GENE-010504-1
Ensembl - ENSDARG00000103176
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NR5A1ENSGALG00000001080Gallus gallus
 NR5A1ENSG00000136931Homo sapiens
 Nr5a1ENSMUSG00000026751Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr5a1b / nuclear receptor subfamily 5, group A, member 1b / NR5A1* / P33242* / Q13285* / Steroidogenic factor 1 * / nuclear receptor subfamily 5 group A member 1*ENSDARG0000002336268
nr5a2 / nuclear receptor subfamily 5, group A, member 2 / O00482*ENSDARG0000010094062
nr5a5 / nuclear receptor subfamily 5, group A, member 5ENSDARG0000003911648
nr1d4a / nuclear receptor subfamily 1, group D, member 4aENSDARG0000003116124
nr1d1 / nuclear receptor subfamily 1, group d, member 1 / P20393* / Q3UV55*ENSDARG0000003316023
nr1d2a / nuclear receptor subfamily 1, group D, member 2aENSDARG0000000382022
nr1d2b / nuclear receptor subfamily 1, group D, member 2b / NR1D2* / Q60674* / Q14995* / nuclear receptor subfamily 1 group D member 2*ENSDARG0000000959422
rorb / RAR-related orphan receptor B / Q8R1B8* / Q92753* / Nuclear receptor ROR-beta *ENSDARG0000003349822
rorca / RAR-related orphan receptor C aENSDARG0000005723122
nr1d4b / nuclear receptor subfamily 1, group D, member 4bENSDARG0000005937022
rorcb / RAR-related orphan receptor C bENSDARG0000001778021
nr6a1b / nuclear receptor subfamily 6, group A, member 1bENSDARG0000001448020
nr6a1a / nuclear receptor subfamily 6, group A, member 1a / NR6A1* / Q64249* / Q15406* / nuclear receptor subfamily 6 group A member 1*ENSDARG0000010150820
rorab / RAR-related orphan receptor A, paralog bENSDARG0000000191019
roraa / RAR-related orphan receptor A, paralog a / RORA* / P51448* / P35398* / RAR related orphan receptor A* / RAR-related orphan receptor alpha*ENSDARG0000003176819
pparaa / peroxisome proliferator-activated receptor alpha a / PPARA* / P23204* / Q07869* / peroxisome proliferator activated receptor alpha*ENSDARG0000003177719
pparab / peroxisome proliferator-activated receptor alpha b / PPARA* / P23204* / Q07869* / peroxisome proliferator activated receptor alpha*ENSDARG0000005432319
pparda / peroxisome proliferator-activated receptor delta a / PPARD* / P35396* / Q03181* / peroxisome proliferator activated receptor delta*ENSDARG0000004452518
ppardb / peroxisome proliferator-activated receptor delta b / PPARD* / P35396* / Q03181* / peroxisome proliferator activated receptor delta*ENSDARG0000000947317
rorc / RAR-related orphan receptor C / P51449* / P51450* / Nuclear receptor ROR-gamma *ENSDARG0000008719510


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR016355  Nuclear hormone receptor family 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0009888 tissue development IBA
 biological_processGO:0021854 hypothalamus development IMP
 biological_processGO:0030325 adrenal gland development IMP
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IBA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IBA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001260 endocrine pancreas endocrine pancreas malformed , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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