ENSDARG00000103494


Danio rerio

Features
Gene ID: ENSDARG00000103494
  
Biological name :usp43a
  
Synonyms : ubiquitin specific peptidase 43a / usp43a
  
Possible biological names infered from orthology : Q70EL4 / Q8BUM9 / ubiquitin specific peptidase 43 / USP43
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 19481394
Gene end: 19665114
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000136694
Ensembl peptide - ENSDARP00000141884
NCBI entrez gene - 563983     See in Manteia.
RefSeq - NM_001089402
RefSeq Peptide - NP_001082871
swissprot - A0A0R4IYE8
swissprot - A0A0R4IPU7
ZFIN ID - ZDB-GENE-100211-1
Ensembl - ENSDARG00000103494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000037812Gallus gallus
 USP43ENSG00000154914Homo sapiens
 Usp43ENSMUSG00000020905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp43b / ubiquitin specific peptidase 43b / USP43* / Q70EL4* / Q8BUM9* / ubiquitin specific peptidase 43*ENSDARG0000008807255
usp31 / ubiquitin specific peptidase 31 / Q70CQ4*ENSDARG0000007401741
usp19 / ubiquitin specific peptidase 19 / O94966* / Q3UJD6*ENSDARG0000000413218
usp4 / ubiquitin specific peptidase 4 (proto-oncogene) / P35123* / Q13107* / ubiquitin specific peptidase 4*ENSDARG0000001477017
usp11 / ubiquitin specific peptidase 11 / P51784* / Q99K46*ENSDARG0000007630317
usp32 / ubiquitin specific peptidase 32 / USP6* / Q8NFA0* / P35125* / ubiquitin specific peptidase 6*ENSDARG0000006189516


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Termination of translesion DNA synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000109 forebrain forebrain bulbous , abnormal
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 ZFA:0000155 somite somite fused with somite , abnormal
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 ZFA:0001094 whole organism whole organism decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region curled , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / complex / reaction
 ENSDARG00000054155 pcna / Q9PTP1 / proliferating cell nuclear antigen / P17918* / P12004* / Pcna-ps2*  / complex / reaction
 ENSDARG00000086374 isg15 / ISG15 ubiquitin-like modifier / P05161* / Q64339* / Ubiquitin-like protein ISG15 *  / complex / reaction






 

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