ENSDARG00000004132


Danio rerio

Features
Gene ID: ENSDARG00000004132
  
Biological name :usp19
  
Synonyms : ubiquitin specific peptidase 19 / usp19
  
Possible biological names infered from orthology : O94966 / Q3UJD6
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 20145300
Gene end: 20177527
  
Corresponding Affymetrix probe sets: Dr.1751.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000116060
Ensembl peptide - ENSDARP00000157435
Ensembl peptide - ENSDARP00000116724
Ensembl peptide - ENSDARP00000100933
NCBI entrez gene - 324335     See in Manteia.
RefSeq - XM_005162118
RefSeq - XM_005162119
swissprot - B7ZDA9
swissprot - B7ZDA8
swissprot - F1RCS0
ZFIN ID - ZDB-GENE-030131-3055
Ensembl - ENSDARG00000004132
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 USP19ENSGALG00000006824Gallus gallus
 USP19ENSG00000172046Homo sapiens
 Usp19ENSMUSG00000006676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
usp4 / ubiquitin specific peptidase 4 (proto-oncogene) / P35123* / Q13107* / ubiquitin specific peptidase 4*ENSDARG0000001477018
usp11 / ubiquitin specific peptidase 11 / P51784* / Q99K46*ENSDARG0000007630318
usp32 / ubiquitin specific peptidase 32 / USP6* / Q8NFA0* / P35125* / ubiquitin specific peptidase 6*ENSDARG0000006189516
usp31 / ubiquitin specific peptidase 31 / Q70CQ4*ENSDARG0000007401714
usp43a / ubiquitin specific peptidase 43a / USP43* / Q70EL4* / Q8BUM9* / ubiquitin specific peptidase 43*ENSDARG0000010349414
usp43b / ubiquitin specific peptidase 43b / USP43* / Q70EL4* / Q8BUM9* / ubiquitin specific peptidase 43*ENSDARG0000008807213


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR002893  Zinc finger, MYND-type
 IPR007052  CS domain
 IPR008978  HSP20-like chaperone
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0021551 central nervous system morphogenesis IMP
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000135 notochord notochord decreased length , abnormal
Show

 ZFA:0000155 somite somite fused with somite , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curled , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000034293 hif1ab / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...  / complex / reaction
 ENSDARG00000006181 hif1aa / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact...  / complex / reaction
 ENSDARG00000044619 birc2 / baculoviral IAP repeat containing 2 / BIRC3* / Q13489* / Q13490* / Q62210* / baculoviral IAP repeat containing 3* / Baculoviral IAP repeat-containing protein 2 *  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr