ENSDARG00000034293
Danio rerio hif1ab factor hypoxia-inducible alpha regulation domain cell dna-templated neuron binding activity pas response migration motor rna polymerase ii sequence-specific dna oxygen-dependent hydroxylation factor- pac motif myc-type basic helix-loop-helix bhlh fold-
Features Gene ID: ENSDARG00000034293 Biological name :hif1ab Synonyms : hif1ab / Possible biological names infered from orthology : HIF1A / / / / Species: Danio rerio Chr. number: 20 Strand: -1 Band: Gene start: 20326611 Gene end: 20355577 Corresponding Affymetrix probe sets: Dr.9052.1.S1_a_at (Zebrafish Array) Cross references: Ensembl peptide - ENSDARP00000004329393202
See in Manteia .
NM_001310042 NP_001296971 Q6EHI4 ZDB-GENE-040426-706 ENSDARG00000034293
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) hif1aa / hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) a / HIF1A* / Q61221* / Q16665* / Hypoxia-inducible factor 1-alpha * / hypoxia inducible fact... ENSDARG00000006181 51 epas1b / endothelial PAS domain protein 1b / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 * ENSDARG00000057671 46 epas1a / endothelial PAS domain protein 1a / EPAS1* / Q99814* / P97481* / endothelial PAS domain protein 1* / Endothelial PAS domain-containing protein 1 * ENSDARG00000008697 45 hif1al / hypoxia-inducible factor 1, alpha subunit, like / HIF3A* / Q9Y2N7* / Q0VBL6* / Hypoxia-inducible factor 3-alpha * / hypoxia inducible factor 3 alpha subunit* ENSDARG00000100826 35 hif1al2 / hypoxia-inducible factor 1, alpha subunit, like 2 ENSDARG00000044550 24 sim1a / single-minded family bHLH transcription factor 1a / SIM1* / Q61045* / P81133* / Single-minded homolog 1 * / single-minded family bHLH transcription factor 1* ENSDARG00000023316 23 NPAS3 / neuronal PAS domain protein 3 / Q8IXF0* ENSDARG00000109820 23 npas1 / neuronal PAS domain protein 1 / P97459* / Q99742* / Neuronal PAS domain-containing protein 1 * ENSDARG00000015876 21 sim1b / single-minded family bHLH transcription factor 1b / SIM1* / Q61045* / P81133* / Single-minded homolog 1 * / single-minded family bHLH transcription factor 1* ENSDARG00000013789 20 arnt2 / aryl-hydrocarbon receptor nuclear translocator 2 / Q61324* / Q9HBZ2* ENSDARG00000103697 16 arntl1a / aryl hydrocarbon receptor nuclear translocator-like 1a / ARNTL* / O00327* / Q9WTL8* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon receptor... ENSDARG00000006791 15 clocka / clock circadian regulator a / CLOCK* / O15516* / O08785* / clock circadian regulator* / Circadian locomoter output cycles protein kaput * ENSDARG00000011703 15 arnt / aryl hydrocarbon receptor nuclear translocator / P27540* / P53762* ENSDARG00000021855 15 arntl1b / aryl hydrocarbon receptor nuclear translocator-like 1b / ARNTL* / O00327* / Q9WTL8* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon receptor... ENSDARG00000035732 15 arntl2 / aryl hydrocarbon receptor nuclear translocator-like 2 / Q2VPD4* / Q8WYA1* / Aryl hydrocarbon receptor nuclear translocator-like protein 2 * ENSDARG00000041381 15 clockb / clock circadian regulator b / CLOCK* / O15516* / O08785* / clock circadian regulator* / Circadian locomoter output cycles protein kaput * ENSDARG00000003631 14 npas2 / neuronal PAS domain protein 2 / Q99743* ENSDARG00000016536 14 CABZ01064671.1 ENSDARG00000039935 12
Protein motifs (from Interpro )Gene Ontology (GO ) response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response to stress response to abiotic stimulus localization of cell movement of cell or subcellular component anatomical structure development cellular developmental process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process response to external stimulus cellular component organization response to chemical cell death response response to stress response response to abiotic stimulus localizatlocalization of cell movement movement of cell or subcellular component anatomicaanatomical structure development cellular cellular developmental process nitrogen nitrogen compound metabolic process biosynthebiosynthetic process cellular cellular metabolic process primary mprimary metabolic process organic sorganic substance metabolic process response response to external stimulus cellular cellular component organization response response to chemical cell deatcell death organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound binding heterocyclic compound binding DNA-binding transcription factor activity chromatin binding protein binding organic cyclic compound bindorganic cyclic compound binding heterocyclic compound bindinheterocyclic compound binding DNA-binding transcription faDNA-binding transcription factor activity chromatin bindingchromatin binding protein bindingprotein binding cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cellcell organelleorganelle
Pathways (from Reactome )Phenotype (from MGI , Zfin or HPO ) ZFA:0000037 anatomical structure anatomical structure amount , ameliorated
Show ZFA:0000152 retina retina increased amount , abnormal
Show ZFA:0001114 head head increased amount , abnormal
Show ZFA:0001115 trunk trunk motor neuron increased amount , abnormal
Show ZFA:0001202 optic cup optic cup increased amount , abnormal
Show ZFA:0001216 splanchnocranium splanchnocranium malformed , abnormal
Show ZFA:0001338 intestine intestine goblet cell decreased amount , abnormal
Show ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta hematopoietic stem cell decreased amount , abnormal
Show ZFA:0005323 ionocyte ionocyte amount , ameliorated
Show ZFA:0009052 motor neuron motor neuron axon guidance decreased process quality , ameliorated
Show ZFA:0009094 goblet cell goblet cell cell maturation disrupted , abnormal
Show
Interacting proteins (from Reactome ) ENSDARG00000004632 egln1b / egl-9 family hypoxia-inducible factor 1b / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1* / complex / reaction ENSDARG00000038576 ube2d1b / ubiquitin-conjugating enzyme E2D 1b / UBE2D1* / P51668* / P61080* / ubiquitin conjugating enzyme E2 D1* / reaction ENSDARG00000038996 egln1a / egl-9 family hypoxia-inducible factor 1a / EGLN1* / Q91YE3* / Q9GZT9* / Egl nine homolog 1 * / egl-9 family hypoxia inducible factor 1* / complex / reaction ENSDARG00000043484 ube2d2 / ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) / P62838* / P62837* / Ube2d2a* / ubiquitin conjugating enzyme E2 D2* / ubiquitin-conjugating enzyme E2D 2A* / reaction ENSDARG00000037980 elob / elongin B / Elobl* / P62869* / Q15370* / complex / reaction ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed* / complex / reaction ENSDARG00000045359 elocb / elongin C paralog b / ELOC* / P83940* / Q15369* / elongin C* / complex / reaction ENSDARG00000013965 cul2 / cullin 2 / Q13617* / Q9D4H8* / complex / reaction ENSDARG00000104609 crebbpa / CREB binding protein a / CREBBP* / Q92793* / CREB binding protein* / complex ENSDARG00000112452 crebbpb / CREB binding protein b / CREBBP* / Q92793* / CREB binding protein* / complex ENSDARG00000021855 arnt / aryl hydrocarbon receptor nuclear translocator / P27540* / P53762* / complex / reaction ENSDARG00000031915 hif1an / P59723 / hypoxia inducible factor 1, alpha subunit inhibitor / Q8BLR9* / Q9NWT6* / Hypoxia-inducible factor 1-alpha inhibitor * / reaction ENSDARG00000059956 ptk6b / PTK6 protein tyrosine kinase 6b / PTK6* / Q64434* / Q13882* / protein tyrosine kinase 6* / PTK6 protein tyrosine kinase 6* / reaction ENSDARG00000062688 gpnmb / glycoprotein (transmembrane) nmb / Q14956* / Q99P91* / glycoprotein nmb* / Transmembrane glycoprotein NMB * / reaction ENSDARG00000075121 hbegfa / heparin-binding EGF-like growth factor a / HBEGF* / Q06186* / Q99075* / heparin binding EGF like growth factor* / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like... / reaction ENSDARG00000004132 usp19 / ubiquitin specific peptidase 19 / O94966* / Q3UJD6* / complex / reaction ENSDARG00000017947 ptk6a / PTK6 protein tyrosine kinase 6a / PTK6* / Q64434* / Q13882* / protein tyrosine kinase 6* / PTK6 protein tyrosine kinase 6* / reaction ENSDARG00000062562 egln2 / egl-9 family hypoxia-inducible factor 2 / Q96KS0* / Q91YE2* / AC008537.1* / Egl nine homolog 2 * / reaction
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