ENSG00000002726


Homo sapiens

Features
Gene ID: ENSG00000002726
  
Biological name :AOC1
  
Synonyms : amine oxidase, copper containing 1 / AOC1 / P19801
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q36.1
Gene start: 150824627
Gene end: 150861504
  
Corresponding Affymetrix probe sets: 203559_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418557
Ensembl peptide - ENSP00000417392
Ensembl peptide - ENSP00000418614
Ensembl peptide - ENSP00000418328
Ensembl peptide - ENSP00000354193
Ensembl peptide - ENSP00000411613
NCBI entrez gene - 26     See in Manteia.
OMIM - 104610
RefSeq - XM_017011945
RefSeq - XM_017011944
RefSeq - NM_001091
RefSeq - NM_001272072
RefSeq - XM_017011947
RefSeq - XM_017011946
RefSeq Peptide - NP_001259001
RefSeq Peptide - NP_001082
swissprot - P19801
swissprot - C9J2J4
swissprot - C9J0G8
Ensembl - ENSG00000002726
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aoc1ENSDARG00000061355Danio rerio
 ENSGALG00000036190Gallus gallus
 1600015I10RikENSMUSG00000029813Mus musculus
 Aoc1ENSMUSG00000029811Mus musculus
 Doxl2ENSMUSG00000068536Mus musculus
 Svs1ENSMUSG00000039215Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AOC2 / O75106 / amine oxidase, copper containing 2ENSG0000013148039
AOC3 / Q16853 / amine oxidase, copper containing 3ENSG0000013147138


Protein motifs (from Interpro)
Interpro ID Name
 IPR000269  Copper amine oxidase
 IPR015798  Copper amine oxidase, catalytic domain
 IPR015800  Copper amine oxidase, N2-terminal
 IPR015802  Copper amine oxidase, N3-terminal
 IPR016182  Copper amine oxidase, N-terminal
 IPR036460  Copper amine oxidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0009308 amine metabolic process IEA
 biological_processGO:0035874 cellular response to copper ion starvation IDA
 biological_processGO:0042493 response to drug IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0046677 response to antibiotic IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071280 cellular response to copper ion IDA
 biological_processGO:0071420 cellular response to histamine IDA
 biological_processGO:0071504 cellular response to heparin TAS
 biological_processGO:0097185 cellular response to azide IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005777 peroxisome NAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005923 bicellular tight junction ISS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome IDA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0008131 primary amine oxidase activity IEA
 molecular_functionGO:0008144 drug binding IDA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048038 quinone binding IEA
 molecular_functionGO:0052597 diamine oxidase activity IEA
 molecular_functionGO:0052598 histamine oxidase activity TAS
 molecular_functionGO:0052599 methylputrescine oxidase activity IEA
 molecular_functionGO:0052600 propane-1,3-diamine oxidase activity IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000002726 AOC1 / P19801 / amine oxidase, copper containing 1  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr