ENSG00000131471


Homo sapiens

Features
Gene ID: ENSG00000131471
  
Biological name :AOC3
  
Synonyms : amine oxidase, copper containing 3 / AOC3 / Q16853
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.31
Gene start: 42851184
Gene end: 42858130
  
Corresponding Affymetrix probe sets: 204894_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000484312
Ensembl peptide - ENSP00000468632
Ensembl peptide - ENSP00000477686
Ensembl peptide - ENSP00000312326
Ensembl peptide - ENSP00000464787
Ensembl peptide - ENSP00000465913
Ensembl peptide - ENSP00000468043
NCBI entrez gene - 8639     See in Manteia.
OMIM - 603735
RefSeq - XM_011525420
RefSeq - NM_001277731
RefSeq - NM_001277732
RefSeq - NM_003734
RefSeq - XM_011525419
RefSeq Peptide - NP_001264661
RefSeq Peptide - NP_003725
RefSeq Peptide - NP_001264660
swissprot - Q16853
swissprot - K7EL47
swissprot - K7EIK5
swissprot - K7EQZ5
Ensembl - ENSG00000131471
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aoc2ENSDARG00000014646Danio rerio
 ENSGALG00000046412Gallus gallus
 ENSGALG00000033522Gallus gallus
 Aoc3ENSMUSG00000019326Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AOC2 / O75106 / amine oxidase, copper containing 2ENSG0000013148065
AOC1 / P19801 / amine oxidase, copper containing 1ENSG0000000272638


Protein motifs (from Interpro)
Interpro ID Name
 IPR000269  Copper amine oxidase
 IPR015798  Copper amine oxidase, catalytic domain
 IPR015800  Copper amine oxidase, N2-terminal
 IPR015802  Copper amine oxidase, N3-terminal
 IPR016182  Copper amine oxidase, N-terminal
 IPR036460  Copper amine oxidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0006954 inflammatory response TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0009308 amine metabolic process IDA
 biological_processGO:0046677 response to antibiotic IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1902283 negative regulation of primary amine oxidase activity IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005507 copper ion binding IDA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008131 primary amine oxidase activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity TAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0048038 quinone binding IDA
 molecular_functionGO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity IEA
 molecular_functionGO:0052594 aminoacetone:oxygen oxidoreductase(deaminating) activity IEA
 molecular_functionGO:0052595 aliphatic-amine oxidase activity IEA
 molecular_functionGO:0052596 phenethylamine:oxygen oxidoreductase (deaminating) activity IEA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131471 AOC3 / Q16853 / amine oxidase, copper containing 3  / complex






 

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