ENSG00000099866


Homo sapiens

Features
Gene ID: ENSG00000099866
  
Biological name :MADCAM1
  
Synonyms : MADCAM1 / mucosal vascular addressin cell adhesion molecule 1 / Q13477
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 489176
Gene end: 505342
  
Corresponding Affymetrix probe sets: 208037_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000372130
Ensembl peptide - ENSP00000475575
Ensembl peptide - ENSP00000484317
Ensembl peptide - ENSP00000484153
Ensembl peptide - ENSP00000483663
Ensembl peptide - ENSP00000480908
Ensembl peptide - ENSP00000480104
Ensembl peptide - ENSP00000215637
Ensembl peptide - ENSP00000304247
NCBI entrez gene - 8174     See in Manteia.
OMIM - 102670
RefSeq - NM_130760
RefSeq - NM_130762
RefSeq Peptide - NP_570116
RefSeq Peptide - NP_570118
swissprot - A0A087WWC0
swissprot - Q13477
swissprot - A0A087X1M5
swissprot - U3KQ59
swissprot - A0A087X1F1
swissprot - A0A087X0U8
swissprot - A0A087WXC9
Ensembl - ENSG00000099866
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000028341Gallus gallus
 Q61826ENSMUSG00000020310Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR015169  Adhesion molecule, immunoglobulin-like
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037413  Mucosal addressin cell adhesion molecule 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002687 positive regulation of leukocyte migration IBA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0030198 extracellular matrix organization TAS
 biological_processGO:0034113 heterotypic cell-cell adhesion IMP
 biological_processGO:0043113 receptor clustering IDA
 biological_processGO:0050776 regulation of immune response TAS
 biological_processGO:0050901 leukocyte tethering or rolling IDA
 biological_processGO:2000403 positive regulation of lymphocyte migration IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0098640 integrin binding involved in cell-matrix adhesion IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000099866 Q13477 / MADCAM1 / mucosal vascular addressin cell adhesion molecule 1  / complex / reaction
 ENSG00000115232 ITGA4 / P13612 / integrin subunit alpha 4  / complex / reaction
 ENSG00000139626 ITGB7 / P26010 / integrin subunit beta 7  / complex / reaction
 ENSG00000188404 SELL / P14151 / selectin L  / complex / reaction






 

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