ENSG00000105388


Homo sapiens

Features
Gene ID: ENSG00000105388
  
Biological name :CEACAM5
  
Synonyms : carcinoembryonic antigen related cell adhesion molecule 5 / CEACAM5 / P06731
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 41708585
Gene end: 41729798
  
Corresponding Affymetrix probe sets: 201884_at (Human Genome U133 Plus 2.0 Array)   217291_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000480800
Ensembl peptide - ENSP00000473252
Ensembl peptide - ENSP00000482157
Ensembl peptide - ENSP00000482303
Ensembl peptide - ENSP00000221992
Ensembl peptide - ENSP00000381600
Ensembl peptide - ENSP00000385072
Ensembl peptide - ENSP00000468997
NCBI entrez gene - 1048     See in Manteia.
OMIM - 114890
RefSeq - XM_017026146
RefSeq - NM_001291484
RefSeq - NM_001308398
RefSeq - NM_004363
RefSeq - XM_005258413
RefSeq - XM_011526322
RefSeq - XM_017026145
RefSeq Peptide - NP_001278413
RefSeq Peptide - NP_001295327
RefSeq Peptide - NP_004354
swissprot - A0A087WYX0
swissprot - M0QX98
swissprot - M0R3J1
swissprot - P06731
swissprot - T2HUW8
swissprot - A0A024R0K5
Ensembl - ENSG00000105388
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-250k15.9ENSDARG00000095134Danio rerio
 Ceacam10ENSMUSG00000054169Mus musculus
 Ceacam11ENSMUSG00000030368Mus musculus
 Ceacam12ENSMUSG00000030366Mus musculus
 Ceacam13ENSMUSG00000057195Mus musculus
 Ceacam14ENSMUSG00000023185Mus musculus
 Ceacam3ENSMUSG00000053228Mus musculus
 P31809ENSMUSG00000074272Mus musculus
 Psg16ENSMUSG00000066760Mus musculus
 Psg17ENSMUSG00000004540Mus musculus
 Psg18ENSMUSG00000003505Mus musculus
 Psg19ENSMUSG00000004542Mus musculus
 Psg20ENSMUSG00000063305Mus musculus
 Psg21ENSMUSG00000070796Mus musculus
 Psg22ENSMUSG00000044903Mus musculus
 Psg23ENSMUSG00000074359Mus musculus
 Psg25ENSMUSG00000070798Mus musculus
 Psg26ENSMUSG00000070799Mus musculus
 Psg27ENSMUSG00000070797Mus musculus
 Psg28ENSMUSG00000030373Mus musculus
 Psg29ENSMUSG00000023159Mus musculus
 Q3UKK2ENSMUSG00000008789Mus musculus
 Q925P2ENSMUSG00000054385Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P13688 / CEACAM1 / carcinoembryonic antigen related cell adhesion molecule 1ENSG0000007938546
P40199 / CEACAM6 / carcinoembryonic antigen related cell adhesion molecule 6ENSG0000008654841
P31997 / CEACAM8 / carcinoembryonic antigen related cell adhesion molecule 8ENSG0000012446937
PSG8 / Q9UQ74 / pregnancy specific beta-1-glycoprotein 8ENSG0000012446727
PSG6 / Q00889 / pregnancy specific beta-1-glycoprotein 6ENSG0000017084827
PSG9 / Q00887 / pregnancy specific beta-1-glycoprotein 9ENSG0000018366826
PSG3 / Q16557 / pregnancy specific beta-1-glycoprotein 3ENSG0000022182626
PSG1 / P11464 / pregnancy specific beta-1-glycoprotein 1ENSG0000023192426
PSG2 / P11465 / pregnancy specific beta-1-glycoprotein 2ENSG0000024222126
PSG11 / Q9UQ72 / pregnancy specific beta-1-glycoprotein 11ENSG0000024313026
PSG4 / Q00888 / pregnancy specific beta-1-glycoprotein 4ENSG0000024313726
Q14002 / CEACAM7 / carcinoembryonic antigen related cell adhesion molecule 7ENSG0000000730625
AC243967.1ENSG0000026788122
CEACAM20 / carcinoembryonic antigen related cell adhesion molecule 20ENSG0000027377721
P40198 / CEACAM3 / carcinoembryonic antigen related cell adhesion molecule 3ENSG0000017095619
PSG5 / Q15238 / pregnancy specific beta-1-glycoprotein 5ENSG0000020494119
Q3KPI0 / CEACAM21 / carcinoembryonic antigen related cell adhesion molecule 21ENSG0000000712918
Q2WEN9 / CEACAM16 / carcinoembryonic antigen related cell adhesion molecule 16ENSG0000021389217
PSG7 / pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)ENSG0000022187816
A8MTB9 / CEACAM18 / carcinoembryonic antigen related cell adhesion molecule 18ENSG0000021382213


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0010832 negative regulation of myotube differentiation IDA
 biological_processGO:0034109 homotypic cell-cell adhesion IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:2000811 negative regulation of anoikis IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071575 integral component of external side of plasma membrane IDA
 molecular_functionGO:0034235 GPI anchor binding IMP
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105388 P06731 / CEACAM5 / carcinoembryonic antigen related cell adhesion molecule 5  / complex






 

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