ENSG00000109576


Homo sapiens

Features
Gene ID: ENSG00000109576
  
Biological name :AADAT
  
Synonyms : AADAT / aminoadipate aminotransferase / Q8N5Z0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q33
Gene start: 170060222
Gene end: 170091699
  
Corresponding Affymetrix probe sets: 223593_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423190
Ensembl peptide - ENSP00000421389
Ensembl peptide - ENSP00000423341
Ensembl peptide - ENSP00000425067
Ensembl peptide - ENSP00000423843
Ensembl peptide - ENSP00000226840
Ensembl peptide - ENSP00000336808
NCBI entrez gene - 51166     See in Manteia.
OMIM - 611754
RefSeq - XM_011532020
RefSeq - NM_001286682
RefSeq - NM_001286683
RefSeq - NM_016228
RefSeq - NM_182662
RefSeq - XM_006714231
RefSeq Peptide - NP_001273612
RefSeq Peptide - NP_872603
RefSeq Peptide - NP_057312
RefSeq Peptide - NP_001273611
swissprot - D6RC56
swissprot - Q8N5Z0
swissprot - D6RFY7
swissprot - D6REB9
swissprot - Q4W5N8
Ensembl - ENSG00000109576
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aadatENSDARG00000011410Danio rerio
 AADATENSGALG00000009655Gallus gallus
 AadatENSMUSG00000057228Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006103 2-oxoglutarate metabolic process IDA
 biological_processGO:0006536 glutamate metabolic process IDA
 biological_processGO:0006554 lysine catabolic process TAS
 biological_processGO:0006569 tryptophan catabolic process TAS
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0019441 tryptophan catabolic process to kynurenine IEA
 biological_processGO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine IEA
 biological_processGO:0070189 kynurenine metabolic process IDA
 biological_processGO:0097052 L-kynurenine metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016212 kynurenine-oxoglutarate transaminase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0047536 2-aminoadipate transaminase activity EXP


Pathways (from Reactome)
Pathway description
Lysine catabolism
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000109576 AADAT / Q8N5Z0 / aminoadipate aminotransferase  / complex






 

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