ENSG00000122958


Homo sapiens

Features
Gene ID: ENSG00000122958
  
Biological name :VPS26A
  
Synonyms : O75436 / VPS26A / VPS26, retromer complex component A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.1
Gene start: 69123512
Gene end: 69172861
  
Corresponding Affymetrix probe sets: 201807_at (Human Genome U133 Plus 2.0 Array)   243316_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000474611
Ensembl peptide - ENSP00000263559
Ensembl peptide - ENSP00000362480
Ensembl peptide - ENSP00000378532
Ensembl peptide - ENSP00000473746
NCBI entrez gene - 9559     See in Manteia.
OMIM - 605506
RefSeq - NM_001318946
RefSeq - NM_001035260
RefSeq - NM_001318944
RefSeq - NM_001318945
RefSeq - NM_004896
RefSeq Peptide - NP_001030337
RefSeq Peptide - NP_001305873
RefSeq Peptide - NP_001305874
RefSeq Peptide - NP_001305875
RefSeq Peptide - NP_004887
swissprot - O75436
swissprot - S4R2Y3
swissprot - S4R3Q6
Ensembl - ENSG00000122958
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6TNP8ENSDARG00000056549Danio rerio
 VPS26AENSGALG00000004174Gallus gallus
 P40336ENSMUSG00000020078Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q4G0F5 / VPS26B / VPS26, retromer complex component BENSG0000015150269


Protein motifs (from Interpro)
Interpro ID Name
 IPR028934  Vacuolar protein sorting protein 26 related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016055 Wnt signaling pathway TAS
 biological_processGO:0016241 regulation of macroautophagy TAS
 biological_processGO:0042147 retrograde transport, endosome to Golgi NAS
 biological_processGO:1990126 retrograde transport, endosome to plasma membrane IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030904 retromer complex NAS
 cellular_componentGO:0030906 retromer, cargo-selective complex NAS
 cellular_componentGO:0031982 vesicle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097422 tubular endosome IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity IBA


Pathways (from Reactome)
Pathway description
WNT ligand biogenesis and trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000112335 SNX3 / O60493 / sorting nexin 3  / complex / reaction
 ENSG00000116729 WLS / Q5T9L3 / wntless Wnt ligand secretion mediator  / complex / reaction
 ENSG00000069329 VPS35 / Q96QK1 / VPS35, retromer complex component  / complex
 ENSG00000111237 VPS29 / Q9UBQ0 / VPS29, retromer complex component  / complex






 

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