ENSG00000125285


Homo sapiens

Features
Gene ID: ENSG00000125285
  
Biological name :SOX21
  
Synonyms : Q9Y651 / SOX21 / SRY-box 21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q32.1
Gene start: 94709622
Gene end: 94712399
  
Corresponding Affymetrix probe sets: 208468_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366144
NCBI entrez gene - 11166     See in Manteia.
OMIM - 604974
RefSeq - NM_007084
RefSeq Peptide - NP_009015
swissprot - Q9Y651
Ensembl - ENSG00000125285
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6RVD7ENSDARG00000008540Danio rerio
 SOX21ENSGALG00000035157Gallus gallus
 Sox21ENSMUSG00000061517Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOX14 / O95416 / SRY-box 14ENSG0000016887558
SOX1 / O00570 / SRY-box 1ENSG0000018296841
SOX3 / P41225 / SRY-box 3ENSG0000013459539
SOX2 / P48431 / SRY-box 2ENSG0000018144937
SOX15 / O60248 / SRY-box 15ENSG0000012919430
SOX11 / P35716 / SRY-box 11ENSG0000017688727
SOX8 / P57073 / SRY-box 8ENSG0000000551325
SOX4 / Q06945 / SRY-box 4ENSG0000012476625
SOX9 / P48436 / SRY-box 9ENSG0000012539825
SOX10 / P56693 / SRY-box 10ENSG0000010014624
SOX17 / Q9H6I2 / SRY-box 17ENSG0000016473623
SOX12 / O15370 / SRY-box 12ENSG0000017773223
SRY / Q05066 / sex determining region YENSG0000018489523
SOX7 / Q9BT81 / SRY-box 7ENSG0000017105621
SOX18 / P35713 / SRY-box 18ENSG0000020388320
AC105001.2ENSG0000025872416


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR022097  Transcription factor SOX
 IPR036910  High mobility group box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001942 hair follicle development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated ISS
 biological_processGO:0006357 regulation of transcription by RNA polymerase II NAS
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0042633 hair cycle IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048863 stem cell differentiation IDA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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