ENSG00000132664


Homo sapiens

Features
Gene ID: ENSG00000132664
  
Biological name :POLR3F
  
Synonyms : POLR3F / Q9H1D9 / RNA polymerase III subunit F
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: p11.23
Gene start: 18467127
Gene end: 18484643
  
Corresponding Affymetrix probe sets: 205218_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000366828
NCBI entrez gene - 10621     See in Manteia.
OMIM - 617455
RefSeq - XM_017027596
RefSeq - NM_001282526
RefSeq - NM_006466
RefSeq - XM_011529141
RefSeq Peptide - NP_001269455
RefSeq Peptide - NP_006457
swissprot - Q9H1D9
Ensembl - ENSG00000132664
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 polr3fENSDARG00000012572Danio rerio
 POLR3FENSGALG00000008749Gallus gallus
 Polr3fENSMUSG00000027427Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007832  RNA polymerase Rpc34
 IPR016049  RNA polymerase Rpc34-like
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006359 regulation of transcription by RNA polymerase III NAS
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0032481 positive regulation of type I interferon production TAS
 biological_processGO:0032728 positive regulation of interferon-beta production IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045089 positive regulation of innate immune response IMP
 biological_processGO:0051607 defense response to virus IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex NAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IDA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity NAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cytosolic sensors of pathogen-associated DNA
RNA Polymerase III Chain Elongation
RNA Polymerase III Transcription Termination
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000186141 POLR3C / Q9BUI4 / RNA polymerase III subunit C  / complex
 ENSG00000121851 Q9BT43 / POLR3GL / RNA polymerase III subunit G like  / complex
 ENSG00000113356 O15318 / POLR3G / RNA polymerase III subunit G  / complex






 

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